公开(公告)号：EP0931088A1

公开(公告)日：1999-07-28

申请号：EP97935607.0

申请日：1997-07-23

申请人： HOECHST MARION ROUSSEL

发明人： AGOURIDAS, Constantin ,  CHANTOT, Jean-François ,  DENIS, Alexis ,  PEJAC, Jean-Marie

IPC分类号： A61K31 ,  A61P31 ,  C07H17

CPC分类号： C07H17/08

摘要： Compounds of formula (I), wherein R is hydrogen, alkyl optionally substituted by halogen or a (CH2)mAr radical or a radical (a), where m is an integer from 1 to 8, each of n and p, which are the same or different, is an integer from 0 to 6, each of A and B, which are the same or different, is hydrogen or halogen or alkyl, and Ar is aryl or heteroaryl, and Z is hydrogen or a carboxylic acid residue; a method for preparing same, and the use of said compounds as drugs, are disclosed.

公开(公告)号：EP0968222A1

公开(公告)日：2000-01-05

申请号：EP98912554.7

申请日：1998-02-26

申请人： HOECHST MARION ROUSSEL

发明人： AGOURIDAS, Constantin ,  CHANTOT, Jean-François ,  DENIS, Alexis ,  FROMENTIN, Claude ,  PEJAC, Jean-Marie

IPC分类号： C07H17/08 ,  A61K31/70

CPC分类号： C07H17/08

摘要： The invention concerns compounds of formula (I) in which A and B form with the atoms to which they are bound a group (a): R1 = NH2, NH-alkyl, NH-alkenyl, NH-alkynyl, (CH2)nAr, NH(CH2)nAr or N=NH(CH2)nAr, Ar = aryl or heteroaryl, optionally substituted; R = H, alkyl optionally substituted, optionally interrupted by one or several heteroatoms, aryl or heteroaryl, optionally substituted, as well as the salts of compounds of formula (I). The compounds of formula (I) have interesting antibiotic properties.