专利检索 ap:("HOECHST MARION ROUSSEL") AND inv:"ROGNON, Valérie" 第 1 页

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发明公开
FORMES CRISTALLINES DU 1S-[1ALPHA(2S*,3R*),9ALPHA]-6,10-DIOXO-N- (2-ETHOXY-5-OXO-TETRAHYDRO-3-FURANYL)-9-[[(1-ISOQUINOLYL)CARBONYL]- AMINO]OCTAHYDRO-6H-PIRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXAMIDE 有权
标题翻译： [[（1-异喹啉 - 1S- [1α的（2S *，3R *），9ALPHA] -6,10-二氧代-N-（2-乙氧基-5-氧代 - 四氢-3-呋喃基）-9的结晶形式）羰基] - 氨基] - 八氢 - 6H-PIRIDAZINO [1,2-A] [1,2]二氮杂-1-甲酰胺

公开(公告)号：EP1070083A1

公开(公告)日：2001-01-24

申请号：EP99911890.4

申请日：1999-04-07

申请人： HOECHST MARION ROUSSEL

发明人： GODARD, Jean-Yves , ROGNON, Valérie

IPC分类号： C07K5/023 , A61K38/06

CPC分类号： C07K5/0202 , A61K38/00

摘要： The invention concerns novel crystalline forms of 1S-[1alpha(2S*, 3R*),9alpha]-6, 10-dioxo-N- (2-ethoxy-5 -oxo-tetrahydro-3 -furanyl)-9-[[( 1-isoquinolyl) carbonyl]-amino] octahydro-6H -piridazino[1, 2-a][1,2]diazepin-1 -carboxamide, anhydrous (form A) and hydrated (form B), the method for preparing them, their use as medicine and the pharmaceutical compositions containing them.