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1.发明公开PROCESSES FOR THE PREPARATION OF (E)-2-FLUOROMETHYLENE-4-(4-FLUOROPHENYL) BUTYLAMINE AND ALKALI METAL SALTS OF DIFORMYLAMIDE 失效用于生产（E）-2-亚甲基FLUOR -4-（4-氟苯基）丁基UNDALKALISALZE DIFORMYLAMIDS作者
公开(公告)号：EP0784604A1
公开(公告)日：1997-07-23
申请号：EP95933834.0
申请日：1995-09-18
发明人： EVANS, Jonathan, C. , GORALSKI, Christian, T. , RAND, Cynthia, L. , VOSEJPKA, Paul, C. , HENTON, Daniel, R.
IPC分类号： C07C , A61K31 , A61P43 , C07C17 , C07C25 , C07C29 , C07C33 , C07C69 , C07C209 , C07C211 , C07C231 , C07C233
CPC分类号： C07C17/16 , C07C25/24 , C07C29/147 , C07C33/483 , C07C69/65 , C07C211/29 , C07C233/13
摘要： The present invention relates to a novel process for preparing (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, also known in the art as (E)-(p-fluorophenethyl)-3-fluoroallylamine, novel intermediates thereof, a novel process for the preparing (E)-2-(fluoromethylene)-4-(p-fluorophenyl)butan-1-ol, a novel process for preparing alkali metal salts of diformylamide, and a novel crystalline form of sodium diformylamide.
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2.发明授权PROCESS FOR THE PREPARATION OF (E)-2-FLUOROMETHYLENE-4-(4-FLUOROPHENYL) BUTAN-1-OL 失效用于生产（E）-2-亚甲基FLUOR -4-（4-氟苯基）丁烷-1- OL
公开(公告)号：EP0784604B1
公开(公告)日：1999-11-17
申请号：EP95933834.4
申请日：1995-09-18
发明人： EVANS, Jonathan, C. , GORALSKI, Christian, T. , RAND, Cynthia, L. , VOSEJPKA, Paul, C. , HENTON, Daniel, R.
CPC分类号： C07C17/16 , C07C25/24 , C07C29/147 , C07C33/483 , C07C69/65 , C07C211/29 , C07C233/13
摘要： The present invention relates to a novel process for preparing (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, also known in the art as (E)-(p-fluorophenethyl)-3-fluoroallylamine, novel intermediates thereof, a novel process for the preparing (E)-2-(fluoromethylene)-4-(p-fluorophenyl)butan-1-ol, a novel process for preparing alkali metal salts of diformylamide, and a novel crystalline form of sodium diformylamide.
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