公开(公告)号：EP4321156A1

公开(公告)日：2024-02-14

申请号：EP22884061.7

申请日：2022-10-20

申请人： Han Wha Pharma Co., Ltd.

发明人： CHAE, Yu Byeong ,  SHIN, Seo Young ,  LIM, Chae Yong ,  OH, Dong Joon

IPC分类号： A61K9/24 ,  A61K9/20 ,  A61K47/20 ,  A61K47/12 ,  A61K9/28 ,  A61K31/47 ,  A61K31/495

摘要： Provided are a tablet comprising: a first drug layer comprising montelukast or a pharmaceutically acceptable salt thereof; a second drug layer comprising levocetirizine or a pharmaceutically acceptable salt thereof; an inner layer being in contact with the first drug layer from one side and in contact with the second drug layer from the other side, such that the first drug layer and the second drug layer are non-contact; and an outer layer comprising the first drug layer, the inner layer, and the second drug layer, and a method for manufacturing the same.
The tablet of the present invention, in which montelukast and levocetirizine are present in a single tablet, but not contacted by a boundary layer, can be usefully used in the pharmaceutical field as a composite formulation that can be manufactured in an efficient process while minimizing drug interactions.