专利检索 ap:("Hangzhou Dac Biotech Co., Ltd") AND inv:"YE, Zhichang" 第 1 页

1.

发明公开
CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES 审中-公开

公开(公告)号：EP3818062A1

公开(公告)日：2021-05-12

申请号：EP18925690.2

申请日：2018-07-05

申请人： Hangzhou Dac Biotech Co., Ltd

发明人： ZHAO, Robert Yongxin , ZHUO, Xiaotao , YANG, Qingliang , ZHAO, Linyao , HUANG, Yuanyuan , YE, Hangbo , YANG, Chengyu , LEI, Jun , GAI, Shun , GUO, Huihui , JIA, Junxiang , BAI, Lu , XIE, Hongsheng , ZHOU, Xiaomai , GUO, Zhixiang , LI, Wenjun , CAO, Mingjun , ZHENG, Jun , YE, Zhichang , YANG, Yanlei

IPC分类号： C07D487/04 , A61K31/5517 , A61P35/00

2.

发明公开
CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS 审中-公开

公开(公告)号：EP3888691A1

公开(公告)日：2021-10-06

申请号：EP21171676.6

申请日：2016-11-14

申请人： Hangzhou Dac Biotech Co., Ltd.

发明人： ZHAO, Yongxin Robert , YANG, Qingliang , HUANG, Yuanyuan , GAI, Shun , YE, Hangbo , ZHAO, Linyao , YANG, Chengyu , GUO, Huihui , ZHOU, Xiaomai , XIE, Hongsheng , ZHU, Haifeng , XU, Yifang , TONG, Qianqian , JIA, Junxiang , CAO, Minjun , LI, Wenjun , GAO, Shuihong , GUO, Zhixiang , BAI, Lu , LI, Chen , YANG, Yanlei , WANG, Chunyan , YE, Zhichang

IPC分类号： A61K47/68 , A61P35/00

摘要： The present invention relates to linkers having a group of propiolyl, substituted acryl (acryloyl), or disubstituted propanoyl, and using such linkers for the conjugation of compounds, in particular, cytotoxic agents to a cell-binding molecule.