Insulinotropic peptide derivative wherein its N-terminal amino acid is modified
    1.
    发明公开
    Insulinotropic peptide derivative wherein its N-terminal amino acid is modified 有权
    胰岛素抵抗剂肽酶修饰剂n末端氨基酸

    公开(公告)号:EP2390265A2

    公开(公告)日:2011-11-30

    申请号:EP11162132.2

    申请日:2008-07-16

    IPC分类号: C07K14/65 C07K14/00

    摘要: The present invention relates to an N-terminal amino acid-modified insulinotropic peptide having a high activity, and to a pharmaceutical composition comprising the same. The insulinotropic peptide derivatives according to the present invention exhibit therapeutic effects, which are not observed in native and other insulinotropic peptide analogs. Therefore, the insulinotropic peptide derivatives and the pharmaceutical composition comprising the same according to the present invention can be effectively provided for the treatment of the diseases.

    摘要翻译: 本发明涉及具有高活性的N-末端氨基酸修饰的促胰岛素肽及其组合物。 根据本发明的促胰岛素肽衍生物显示出在天然和其他促胰岛素肽类似物中未观察到的治疗效果。 因此,可以有效地提供促胰岛素肽衍生物和包含其的本发明的药物组合物用于治疗疾病。