公开(公告)号：EP4269395A1

公开(公告)日：2023-11-01

申请号：EP21911371.9

申请日：2021-12-14

申请人： Hanmi Pharmaceutical Co., Ltd.

发明人： CHOI, Jae Yul ,  KIM, Won Jeoung ,  KIM, Ji Sook ,  KIM, Min Jeong ,  PARK, Won Gi ,  AHN, Young Gil ,  BAE, In Hwan

IPC分类号： C07D239/94 ,  A61K31/5377 ,  A61K31/517 ,  A61P35/00 ,  C07D403/04 ,  C07D405/12 ,  C07D409/12

摘要： The present invention relates to a novel quinazoline derivative compound as a SOS1 inhibitor and to uses thereof. More particularly, the present invention relates to a novel quinazoline derivative compound having inhibitory activity on SOS1 binding to RAS family proteins and/or RAC1, to pharmacologically acceptable salts thereof, and to pharmaceutical compositions comprising such compounds.