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1.发明公开Insulinotropic peptide derivative wherein its N-terminal amino acid is modified 有权其N-末端氨基酸被修饰的促胰岛素肽衍生物
公开(公告)号：EP2537860A1
公开(公告)日：2012-12-26
申请号：EP12185370.9
申请日：2008-07-16
发明人： Kim, Young Hoon , Jung, Sung Youb , Kwon, Se Chang , Bae, Sung Min , Lee, Gwan Sun , Song, Dae Hae , Lim, Chang Ki
CPC分类号： C07K14/46 , A61K38/26 , C07K14/57563 , C07K14/605
摘要： The present invention relates to an N-terminal amino acid-modified insulinotropic peptide having a high activity, and to a pharmaceutical composition comprising the same. The insulinotropic peptide derivatives according to the present invention exhibit therapeutic effects, which are not observed in native and other insulinotropic peptide analogs. Therefore, the insulinotropic peptide derivatives and the pharmaceutical composition comprising the same according to the present invention can be effectively provided for the treatment of the diseases.
摘要翻译： 本发明涉及具有高活性的N-末端氨基酸修饰的促胰岛素肽以及包含其的药物组合物。 根据本发明的促胰岛素肽衍生物显示治疗效果，这在天然和其他促胰岛素肽类似物中未观察到。 因此，根据本发明的促胰岛素肽衍生物和包含其的药物组合物可以有效地提供用于治疗疾病。
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2.发明授权Insulinotropic peptide derivative wherein its N-terminal amino acid is modified 有权其N-末端氨基酸被修饰的促胰岛素肽衍生物
公开(公告)号：EP2537860B1
公开(公告)日：2014-11-26
申请号：EP12185370.9
申请日：2008-07-16
发明人： Kim, Young Hoon , Jung, Sung Youb , Kwon, Se Chang , Bae, Sung Min , Lee, Gwan Sun , Song, Dae Hae , Lim, Chang Ki
CPC分类号： C07K14/46 , A61K38/26 , C07K14/57563 , C07K14/605
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3.发明授权Insulinotropic peptide derivative wherein its n-terminal amino acid is modified 有权具有修饰的N-末端氨基酸促胰岛素肽衍生物
公开(公告)号：EP2537861B1
公开(公告)日：2014-11-26
申请号：EP12185376.6
申请日：2008-07-16
发明人： Kim, Young Hoon , Jung, Sung Youb , Kwon, Se Chang , Bae, Sung Min , Lee, Gwan Sun , Song, Dae Hae , Lim, Chang Ki
CPC分类号： C07K14/46 , A61K38/26 , C07K14/57563 , C07K14/605
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4.发明授权Insulinotropic peptide derivative wherein its N-terminal amino acid is modified 有权具有修饰的N-末端氨基酸促胰岛素肽衍生物
公开(公告)号：EP2390265B1
公开(公告)日：2013-11-06
申请号：EP11162132.2
申请日：2008-07-16
发明人： Song, Dae Hae , Lim, Chang Ki , Kim, Young Hoon , Kwon, Se Chang , Lee, Gwan Sun , Bae, Sung Min , Jung, Sung Youb
CPC分类号： C07K14/46 , A61K38/26 , C07K14/57563 , C07K14/605
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5.发明公开Insulinotropic peptide derivative wherein its n-terminal amino acid is modified 有权具有修饰的N-末端氨基酸促胰岛素肽衍生物
公开(公告)号：EP2537861A1
公开(公告)日：2012-12-26
申请号：EP12185376.6
申请日：2008-07-16
发明人： Kim, Young Hoon , Jung, Sung Youb , Kwon, Se Chang , Bae, Sung Min , Lee, Gwan Sun , Song, Dae Hae , Lim, Chang Ki
CPC分类号： C07K14/46 , A61K38/26 , C07K14/57563 , C07K14/605
摘要： The present invention relates to an N-terminal amino acid-modified insulinotropic peptide having a high activity, and to a pharmaceutical composition comprising the same. The insulinotropic peptide derivatives according to the present invention exhibit therapeutic effects, which are not observed in native and other insulinotropic peptide analogs. Therefore, the insulinotropic peptide derivatives and the pharmaceutical composition comprising the same according to the present invention can be effectively provided for the treatment of the diseases.
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