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1.发明授权COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A CANINE 有权组合物和方法用于诊断和肾脏疾病在狗治疗
公开(公告)号：EP2517020B1
公开(公告)日：2015-10-21
申请号：EP10807768.6
申请日：2010-12-23
IPC分类号： G01N33/68
CPC分类号： G01N33/50 , C12Q1/6883 , C12Q2600/158 , G01N2800/347
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2.发明公开COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A CANINE 有权组合物和方法用于诊断和肾脏疾病在狗治疗
公开(公告)号：EP2517020A2
公开(公告)日：2012-10-31
申请号：EP10807768.6
申请日：2010-12-23
IPC分类号： G01N33/68
CPC分类号： G01N33/50 , C12Q1/6883 , C12Q2600/158 , G01N2800/347
摘要： The present invention provides methods for: diagnosing of, devising and monitoring a treatment plan for, and monitoring the status of a kidney disorder characterized by an abnormal loss of renal function, renal failure, reduced glomerular filtration rate or glomerulonephritis, in a canine, wherein the kidney disorder is detectable by utilizing at least one relevant biomarker isolated and measured from a biological test sample taken from such canine. The invention additionally relates to compositions, reagents and kits for carrying out the specified methods.
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3.发明授权COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A FELINE 有权组合物和方法来诊断和肾脏病的猫治疗
公开(公告)号：EP2678687B1
公开(公告)日：2015-09-02
申请号：EP11713396.7
申请日：2011-02-24
CPC分类号： C12Q1/6883 , A23K50/40 , C12Q2600/112 , G01N33/6893 , G01N2800/347
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4.发明公开METHODS OF DIAGNOSIS, CONTROL AND PROPHYLAXIS OF INFLAMMATION AND MITIGATION OF INFLAMMATORY CONDITIONS IN FELINES 有权方法诊断，在猫控制和炎症PROPHYLASE和弱化炎症的疾病的
公开(公告)号：EP2568823A1
公开(公告)日：2013-03-20
申请号：EP11720682.1
申请日：2011-05-09
CPC分类号： C12Q1/6809 , A23K20/147 , A23K20/158 , A23K20/174 , A23K20/30 , A23K50/40
摘要： The invention relates to methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions, particularly arthritis and joint pain, in felines, comprising measuring particular inflammatory biomarkers. The invention further provides a method to treat or control inflammation comprising administering a diet comprising increased levels of one or more of DHA, EPA, methionine, manganese, vitamin C, vitamin E, and/or L-carnitine.
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5.发明授权METHODS OF DIAGNOSIS, CONTROL AND PROPHYLAXIS OF INFLAMMATION AND MITIGATION OF INFLAMMATORY CONDITIONS IN FELINES 有权方法诊断，在猫控制和炎症PROPHYLASE和弱化炎症的疾病的
公开(公告)号：EP2568823B1
公开(公告)日：2016-04-27
申请号：EP11720682.1
申请日：2011-05-09
CPC分类号： C12Q1/6809 , A23K20/147 , A23K20/158 , A23K20/174 , A23K20/30 , A23K50/40
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6.发明公开COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A FELINE 有权组合物和方法来诊断和肾脏病的猫治疗
公开(公告)号：EP2678687A1
公开(公告)日：2014-01-01
申请号：EP11713396.7
申请日：2011-02-24
IPC分类号： G01N33/68
CPC分类号： C12Q1/6883 , A23K50/40 , C12Q2600/112 , G01N33/6893 , G01N2800/347
摘要： The present invention provides a method of diagnosing the existence of a kidney disorder in a feline comprising measuring the level of expression of one or more biomarkers selected from the group consisting of lumican; collagen alpha 1 (111) chain, variant 12; decorin; secreted frizzled-related protein 2; retinol binding protein 5; MMP-2; MMP-7; and MMP- 19, in a biological sample from the feline, wherein differences in expression of the one or more biomarkers in the sample relative to a control value for expression in a sample from a normal animal indicate the existence of a kidney disorder; a method of treating a feline so diagnosed; and compositions, reagents and kits for carrying out the specified methods.
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