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10 条记录 (耗时 0.016 秒)

    ADHESIVE PLASTER
    1.
    发明公开
    ADHESIVE PLASTER 审中-公开
    胶粘剂

    公开(公告)号：EP3266451A1

    公开(公告)日：2018-01-10

    申请号：EP16758781.5

    申请日：2016-02-22

    申请人： Hisamitsu Pharmaceutical Co., Inc.

    发明人： FUJIWARA, Yoko ,  YASUKOCHI, Takashi ,  TAKAGI, Yuka

    IPC分类号： A61K9/70 ,  A61K47/12 ,  A61K47/14 ,  A61K47/32 ,  A61K47/34

    摘要： A patch includes an adhesive layer and a release liner laminated on at least one surface of a backing. The adhesive layer comprises, as an adhesive base agent, at least one selected from the group consisting of acrylate-based adhesives and rubber-based adhesives, and the adhesive layer comprises 0.3 to 5% by mass of a nonfunctional silicone oil having a kinematic viscosity of 10 to 350 cSt at 25°C.

    摘要翻译： 贴片包括层压在背衬的至少一个表面上的粘合剂层和剥离衬垫。 所述粘合剂层包含选自由丙烯酸酯类粘合剂和橡胶类粘合剂组成的组中的至少一种作为粘合剂基剂，并且所述粘合剂层包含0.3至5质量％的具有运动粘度 在25℃下为10至350cSt。

    ASENAPINE-CONTAINING ADHESIVE PATCH
    2.
    发明公开
    ASENAPINE-CONTAINING ADHESIVE PATCH 审中-公开

    公开(公告)号：EP3861998A1

    公开(公告)日：2021-08-11

    申请号：EP19868311.2

    申请日：2019-09-25

    申请人： Hisamitsu Pharmaceutical Co., Inc.

    发明人： YUKUHIRO, Masaki ,  TAKAGI, Yuka ,  MICHINAKA, Yasunari

    IPC分类号： A61K31/407 ,  A61K9/70 ,  A61K47/02 ,  A61K47/12 ,  A61K47/32 ,  A61K47/34 ,  A61P25/18

    摘要： An object of the present invention is to provide an asenapine-containing patch having excellent sustained-release properties while enhancing skin permeability by using a silicone-based pressure-sensitive adhesive base. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and/or a pharmaceutically acceptable salt thereof, a silicone-based pressure-sensitive adhesive base and a release control agent, and the ratio of the maximum skin permeation rate of asenapine to the minimum skin permeation rate from the time when the maximum skin permeation rate is reached to 24 hours is less than 1.62.

    SKIN PATCH
    5.
    发明公开
    SKIN PATCH 审中-公开
    皮肤补丁

    公开(公告)号：EP2907515A1

    公开(公告)日：2015-08-19

    申请号：EP13845905.2

    申请日：2013-10-08

    申请人： Hisamitsu Pharmaceutical Co., Inc.

    发明人： UMEMOTO, Takuya ,  TAKAGI, Yuka ,  MICHINAKA, Yasunari

    IPC分类号： A61K31/551 ,  A61K9/70 ,  A61K47/06 ,  A61K47/12 ,  A61K47/32 ,  A61K47/34 ,  A61P37/08 ,  A61P43/00

    CPC分类号： A61K47/12 ,  A61K9/7053 ,  A61K9/7061 ,  A61K9/7069 ,  A61K31/551

    摘要： A patch comprising a support layer and an adhesive agent layer, wherein the adhesive agent layer comprises at least one drug selected from the group consisting of emedastine and pharmaceutically acceptable salts thereof , at least one adhesive agent selected from the group consisting of rubber-based adhesive agents and silicone-based adhesive agents, and an alkali metal fumarate as a cohesive force-improving agent for the adhesive agent layer.

    摘要翻译： 1。一种贴剂，其包含支撑层和粘合剂层，其中所述粘合剂层包含选自以下的至少一种药物：厄美斯汀及其药学上可接受的盐，至少一种选自橡胶基粘合剂 试剂和有机硅基粘合剂，以及富马酸碱金属盐作为粘合剂层的粘合力改进剂。

    ASENAPINE-CONTAINING ADHESIVE PATCH
    6.
    发明公开
    ASENAPINE-CONTAINING ADHESIVE PATCH 审中-公开

    公开(公告)号：EP3861999A1

    公开(公告)日：2021-08-11

    申请号：EP19869454.9

    申请日：2019-09-25

    申请人： Hisamitsu Pharmaceutical Co., Inc.

    发明人： YUKUHIRO, Masaki ,  TAKAGI, Yuka ,  AMANO, Satoshi

    IPC分类号： A61K31/407 ,  A61K9/70 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/22 ,  A61K47/34 ,  A61P25/18

    摘要： An object of the present invention is to provide an asenapine-containing patch having excellent adhesiveness and handleability, which can persistently provide sufficient medicinal effects by suppressing cold flow during storage or application while enhancing skin permeability using a silicone-based pressure-sensitive adhesive base, and thereby maintaining the stability of the drug in the patch during storage, and maintaining an appropriate administration form for a long period of time. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and a silicone-based pressure-sensitive adhesive base, and the loss tangent (tan δ) of the pressure-sensitive adhesive layer is 0.75 to 1.5 at 1.0 Hz.