公开(公告)号：EP3099364A1

公开(公告)日：2016-12-07

申请号：EP16722343.7

申请日：2016-04-28

申请人： Hovione Technology Limited

发明人： VENTURA, Joao ,  VILLAX, Peter ,  FARIA, Cristina

IPC分类号： A61M15/00

CPC分类号： A61M15/002 ,  A61K9/0075 ,  A61M15/0021 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0086 ,  A61M2202/064

摘要： A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body 801 and a cartridge 803 with at least one powder compartment 805 including one dose of a drug. The body has an opening 804 shaped for receiving the cartridge 803 and the means to allow a controlled sliding movement of the cartridge 803 relative to the body 801 after mounting. The cartridge powder compartment 805 comprises at least two inlets or slits 806, 809, at least one of which is a side inlet 809, for the admission of air, and a compartment outlet 807 to allow filling and fluid communication with an inhalation channel 808 provided in the body 801. In use, the patient slides the cartridge 803 relative to the body 801 from the storage position, where the inlets in the cartridge powder compartment 805 are blocked and sealed by walls comprised in the body 801, into the inhalation position, where the compartment inlets become available for the admission of air used in the dispersion of the particles there contained and the compartment outlet 807 becomes aligned with the inhalation channel 808 in the body 801 to allow the entrainment of the dose dispersed through the device and into the desired site of action during inhalation. The addition of one or more lateral vents 809 in the cartridge powder compartments induces a turbulent and swirling flow pattern that promotes improved dispersion and entrainment. The invention affords a very economical and simple device for the delivery of high dosages of inhaled medicines.

摘要翻译： 一种用于肺或鼻用的干粉吸入器，至少包括吸入器主体（801）和具有至少一个包含一剂药物的粉末隔室（805）的药筒（803）。 主体具有形状用于接收盒（803）的开口（804）和用于在安装之后允许盒（803）相对于主体（801）受到控制的滑动运动的装置。 墨粉盒隔室（805）包括至少两个入口或狭缝（806,809），其至少一个是用于容纳空气的侧入口（809），以及隔室出口（807），以允许填充和 与设置在身体（801）中的吸入通道（808）流体连通。 在使用中，患者相对于身体（801）相对于身体（801）滑动，其中药筒粉末隔室（805）中的入口被包含在身体（801）中的壁被阻塞和密封， 吸入位置，其中隔室入口变得可用于容纳在其中包含的颗粒的分散体中使用的空气，并且隔室出口（807）变得与主体（801）中的吸入通道（808）对准，以允许夹带 剂量在吸入期间分散通过装置并进入所需的作用位置。 在筒式粉末隔室中添加一个或多个侧向通风口（809）引起湍流和涡流模式，其促进改进的分散和夹带。 本发明提供了用于递送高剂量吸入药物的非常经济且简单的装置。

公开(公告)号：EP3890811A1

公开(公告)日：2021-10-13

申请号：EP19809409.6

申请日：2019-11-20

申请人： Hovione Technology Limited

发明人： VENTURA, João ,  VILLAX, Peter ,  CARVALHO, Agostinho ,  CARAMELO, Daniel ,  JOSUÉ, Sónia

IPC分类号： A61M15/00

公开(公告)号：EP3131611B1

公开(公告)日：2019-03-27

申请号：EP15720216.9

申请日：2015-04-29

申请人： Hovione Technology Limited

发明人： MCDERMENT, Ian ,  VILLAX, Peter ,  VENTURA, João ,  RICHARDSON, William

IPC分类号： A61M15/00 ,  A61M15/08

公开(公告)号：EP3099364B1

公开(公告)日：2017-11-22

申请号：EP16722343.7

申请日：2016-04-28

申请人： Hovione Technology Limited

发明人： VENTURA, Joao ,  VILLAX, Peter

IPC分类号： A61M15/00

CPC分类号： A61M15/002 ,  A61K9/0075 ,  A61M15/0021 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0086 ,  A61M2202/064

摘要： A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body 801 and a cartridge 803 with at least one powder compartment 805 including one dose of a drug. The body has an opening 804 shaped for receiving the cartridge 803 and the means to allow a controlled sliding movement of the cartridge 803 relative to the body 801 after mounting. The cartridge powder compartment 805 comprises at least two inlets or slits 806, 809, at least one of which is a side inlet 809, for the admission of air, and a compartment outlet 807 to allow filling and fluid communication with an inhalation channel 808 provided in the body 801. In use, the patient slides the cartridge 803 relative to the body 801 from the storage position, where the inlets in the cartridge powder compartment 805 are blocked and sealed by walls comprised in the body 801, into the inhalation position, where the compartment inlets become available for the admission of air used in the dispersion of the particles there contained and the compartment outlet 807 becomes aligned with the inhalation channel 808 in the body 801 to allow the entrainment of the dose dispersed through the device and into the desired site of action during inhalation. The addition of one or more lateral vents 809 in the cartridge powder compartments induces a turbulent and swirling flow pattern that promotes improved dispersion and entrainment. The invention affords a very economical and simple device for the delivery of high dosages of inhaled medicines.

公开(公告)号：EP3131611A1

公开(公告)日：2017-02-22

申请号：EP15720216.9

申请日：2015-04-29

申请人： Hovione Technology Limited

发明人： MCDERMENT, Ian ,  VILLAX, Peter ,  VENTURA, João ,  RICHARDSON, William

IPC分类号： A61M15/00

CPC分类号： A61M15/0026 ,  A61M15/0028 ,  A61M15/0038 ,  A61M15/004 ,  A61M15/0091 ,  A61M15/08 ,  A61M2202/064 ,  A61M2207/00

摘要： A dry powder inhaler (1) for pulmonary or nasal use, employing capsules (6) containing a dose of powder for inhalation, comprising four components: a capsule tray (2), a cover (4) and a mouthpiece (8) and an inhaler body (3). Air is drawn by the patient via the mouthpiece (8) which is in communication with the capsule (6) and travels via air paths through the device (1) and through the capsule (6) thereby dispersing and entraining the dose of powder. The capsule (6) is cut by cutting means (18, 19) located on the body (3). The inhaler body (3), the mouthpiece (8) and the cover (4) are provided with hinge segments (20, 35, 42) which when assembled together and the mouthpiece (8) is locked into the body (3), form a single hinge (5) and which allows the cover (4) to freely pivot around the body (3) and the mouthpiece (8).

摘要翻译： 1，一种用于肺部或鼻部使用的干粉吸入器（1），采用含有一定剂量粉末吸入的胶囊（6），包括四个部件：一个胶囊托盘（2），一个盖子（4）和一个吹嘴（8）以及一个 吸入器体（3）。 患者经由与胶囊（6）连通并通过空气路径穿过装置（1）并穿过胶囊（6）的吹口（8）吸入空气，由此分散和携带一定剂量的粉末。 胶囊（6）由位于主体（3）上的切割装置（18,19）切割。 吸入器本体（3），吹嘴（8）和盖（4）设有铰链段（20,35,42），当组装在一起并且吹嘴（8）锁定到本体（3）中时，形成 一个单一的铰链（5），并允许盖子（4）围绕主体（3）和咬嘴（8）自由转动。