专利检索 ap:("Hubei Bio-Pharmaceutical Industrial Technological Institute Inc." OR "Humanwell Healthcare (Group) Co., Ltd.") AND inv:"LI, Gang" 第 1 页

1.

发明授权
ANALOGUES OF 4H-PYRAZOLO[1,5- ]BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS 有权

公开(公告)号：EP3130592B1

公开(公告)日：2019-08-14

申请号：EP15777444.9

申请日：2015-03-30

申请人： Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. , Humanwell Healthcare (Group) Co., Ltd.

发明人： DING, Zhaozhong , CHEN, Shuhui , LI, Gang , WANG, Cailin , ZHANG, Zhibo , TU, Ronghua , WANG, Cailin , YUE, Yang , ZHANG, Zhibo , CHEN, Hailiang , SUN, Wenjie , HUANG, Lu

IPC分类号： C07D487/04 , C07D519/00 , A61P35/00 , A61P25/00 , A61P9/10 , A61P29/00 , A61P3/10

2.

发明公开
ANALOGUES OF 4H-PYRAZOLO[1,5- ]BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS 审中-公开
标题翻译： ANALOGA EINER 4H-PYRAZOLO [1,5-A]苯并咪唑-VERBINDUNG ALS PARP-HEMMER

公开(公告)号：EP3130592A1

公开(公告)日：2017-02-15

申请号：EP15777444.9

申请日：2015-03-30

申请人： Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. , Humanwell Healthcare (Group) Co., Ltd. , Medshine Discovery Inc.

发明人： DING, Zhaozhong , CHEN, Shuhui , LI, Gang , WANG, Cailin , ZHANG, Zhibo , TU, Ronghua , WANG, Cailin , YUE, Yang , ZHANG, Zhibo , CHEN, Hailiang , SUN, Wenjie , HUANG, Lu

IPC分类号： C07D487/04 , C07D519/00 , A61P35/00 , A61P25/00 , A61P9/10 , A61P29/00 , A61P3/10

CPC分类号： C07D487/04 , C07D519/00

摘要： Disclosed is a series of analogues of 4H-pyrazolo[1,5-a]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.

摘要翻译： 公开了一系列4H-吡唑并[1,5-a]苯并咪唑化合物的类似物作为PARP抑制剂。特别地，本发明中公开的是式（I）所示的化合物或其药学上可接受的盐作为PARP抑制剂。

3.

发明公开
SALT TYPE AND CRYSTAL TYPE OF 4H-PYRAZOLO [1, 5-ALPHA]BENZIMIDAZOLE COMPOUND AND PREPARATION METHOD AND INTERMEDIATE THEREOF 审中-公开

公开(公告)号：EP3357925A1

公开(公告)日：2018-08-08

申请号：EP16850379.5

申请日：2016-09-29

申请人： Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. , Humanwell Healthcare (Group) Co., Ltd. , Medshine Discovery Inc.

发明人： WANG, Xuehai , DING, Charles Z. , SHEN, Jie , CHEN, Shuhui , LI, Lie , LI, Gang , XU, Yong , WANG, Cailin , TU, Ronghua , WANG, Jimeng , YUE, Yang , DENG, Biao , CHEN, Hailiang , LIU, Hui , SUN, Wenjie , WANG, Cong , HUANG, Lu , WANG, Zheng , LI, Weidong

IPC分类号： C07D487/04 , C07D401/04 , A61P35/00

CPC分类号： C07D487/04 , C07B2200/13 , C07C57/145 , C07D401/04

摘要： Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof.