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    TUMOR CHEMOTHERAPEUTIC DRUG FORMULATION AND PREPARATION METHOD THEREOF
    1.
    发明公开
    TUMOR CHEMOTHERAPEUTIC DRUG FORMULATION AND PREPARATION METHOD THEREOF 有权
    肿瘤化疗药物制剂及其制备方法

    公开(公告)号：EP2749292A1

    公开(公告)日：2014-07-02

    申请号：EP12825203.8

    申请日：2012-01-19

    申请人： Hubei Soundny Biotechnology Co., Ltd. ,  Huang, Bo

    发明人： HUANG, Bo

    IPC分类号： A61K47/46 ,  A61K45/00 ,  A61P35/00

    CPC分类号： A61K9/127 ,  A61K9/0019 ,  A61K9/5068 ,  A61K9/5089 ,  A61K31/519 ,  A61K31/704 ,  A61K33/24 ,  A61K35/13 ,  A61K45/06 ,  A61K2300/00

    摘要： The present invention provides a pharmaceutical preparation for tumor chemotherapy and a method for producing the same, the pharmaceutical preparation for tumor chemotherapy comprises cell vesicles derived from apoptotic tumor cells and chemotherapeutic drugs as active ingredients wrapped within the cell vesicles. The chemotherapeutic drugs contained within the pharmaceutical preparation are chemotherapeutic drugs containing active ingredients for the treatment of the tumors from which the cell vesicles are provided. The present invention also provides a method for producing the pharmaceutical preparation for tumor chemotherapy. The technical solutions provided by the present invention can selectively release the chemotherapeutic drugs to the tumor sites and maintain lasting medicinal effect, increasing their killing effects against tumor cells and reducing the toxic side-effect of the chemotherapeutic drugs to normal cells.

    摘要翻译： 本发明提供用于肿瘤化疗的药物制剂及其制备方法，用于肿瘤化疗的药物制剂包含源自凋亡肿瘤细胞的细胞囊泡和化疗药物作为包裹在细胞囊泡内的活性成分。 包含在药物制剂中的化学治疗药物是含有活性成分的化疗药物，用于治疗提供细胞囊泡的肿瘤。 本发明还提供了一种生产肿瘤化疗药物制剂的方法。 本发明提供的技术方案能够选择性地将化疗药物释放到肿瘤部位，保持药效持久，增强对肿瘤细胞的杀伤作用，降低化疗药物对正常细胞的毒副作用。

    ONCOLYTIC VIRUS FORMULATION AND PREPARATION METHOD THEREOF
    2.
    发明公开
    ONCOLYTIC VIRUS FORMULATION AND PREPARATION METHOD THEREOF 审中-公开
    溶瘤病毒制剂及其制备方法

    公开(公告)号：EP3305310A1

    公开(公告)日：2018-04-11

    申请号：EP16802374.5

    申请日：2016-03-30

    申请人： Hubei Soundny Biotechnology Co., Ltd.

    发明人： HUANG, Bo

    IPC分类号： A61K35/76 ,  C12N7/00 ,  A61P35/00

    摘要： The present invention provides an oncolytic virus formulation and preparation method thereof. The oncolytic virus formulation comprises cell vesicles derived from apoptotic tumor cells and oncolytic viruses coated in the cell vesicles as an effective component. The oncolytic virus formulation uses cell vesicles derived from tumor cells themselves to coat the oncolytic viruses, so as to evade the body's immune system attack and can be targeted to the tumor treatment site, and improve the tumor-killing effect.

    摘要翻译： 本发明提供了一种溶瘤病毒制剂及其制备方法。 溶瘤病毒制剂包含源自凋亡肿瘤细胞的细胞囊泡和包被在细胞囊泡中的溶瘤病毒作为有效成分。 溶瘤病毒制剂使用来自肿瘤细胞本身的细胞囊泡涂布溶瘤病毒，以逃避机体的免疫系统攻击并可靶向肿瘤治疗部位，并提高肿瘤杀伤效果。