公开(公告)号：EP1428833A2

公开(公告)日：2004-06-16

申请号：EP04001119.9

申请日：1998-06-04

申请人： Human Genome Sciences, Inc.

发明人： Young, Paul ,  Greene, John M. ,  Ferrie, Ann M. ,  Ruben, Steven M. ,  Rosen, Craig A. ,  Hu, Jing-Shan ,  Olsen, Henrik S. ,  Ebner, Reinhard ,  Brewer, Laurie A. ,  More, Paul A. ,  Shi, Yanggu ,  Florence, Charles ,  Florence, Kimberly ,  LaFleur, David W. ,  Ni, Jian ,  Fan, Ping ,  Wei, Ying-Fei ,  Fischer, Carrie L. ,  Soppet, Daniel R. ,  Li, Yi ,  Zeng, Zhizhen ,  Kyaw, Hla ,  Yu, Guo-Liang ,  Feng, Ping ,  Dillon, Patrick J. ,  Endress, Gregory A. ,  Carter, Kenneth C.

IPC分类号： C07K14/435 ,  C12N1/20 ,  C12N15/00 ,  C12N15/09 ,  C12N15/63 ,  G01N33/53 ,  A61K38/17 ,  A61K39/395 ,  A61K48/00

CPC分类号： C07K14/47

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regionsof the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。