-
1.发明公开Inclusion complexes with silybinin, their preparation and pharmaceutical compositions containing them 失效包括与SILYBININ，他们的制剂和含有他们的药物组合物的复合物
公开(公告)号：EP0422497A3
公开(公告)日：1991-08-14
申请号：EP90118964.7
申请日：1990-10-04
发明人： Valcavi, Umberto, Prof. , Monterosso, Vincenzo, Dr. , Caponi, Roberto, Dr. , Bosone, Enrico, Dr. , Wachter, Wilfried Peter, Dr. rer. nat. , Szejtli, Jozsef, Prof. Dr.
IPC分类号： C08B37/16 , A61K31/735
CPC分类号： C08B37/0015
摘要： The invention relates to novel inclusion complexes of Silybinin with a cyclodextrin selected from the group consisting of α-, β- and γ-cyclodextrin and a suitable derivative thereof and to the method for the preparation thereof. The novel inclusion complexes of Silybinin showed a highly improved bioavailability in comparison to Silybinin which makes them particularly interesting in the treatment of various hepatotoxic conditions.
-
2.发明公开Inclusion complexes with silybinin, their preparation and pharmaceutical compositions containing them 失效包合配合物与Silybinin，它们的制备和含有它们的药物制剂。
公开(公告)号：EP0422497A2
公开(公告)日：1991-04-17
申请号：EP90118964.7
申请日：1990-10-04
发明人： Valcavi, Umberto, Prof. , Monterosso, Vincenzo, Dr. , Caponi, Roberto, Dr. , Bosone, Enrico, Dr. , Wachter, Wilfried Peter, Dr. rer. nat. , Szejtli, Jozsef, Prof. Dr.
IPC分类号： C08B37/16 , A61K31/735
CPC分类号： C08B37/0015
摘要： The invention relates to novel inclusion complexes of Silybinin with a cyclodextrin selected from the group consisting of α-, β- and γ-cyclodextrin and a suitable derivative thereof and to the method for the preparation thereof. The novel inclusion complexes of Silybinin showed a highly improved bioavailability in comparison to Silybinin which makes them particularly interesting in the treatment of various hepatotoxic conditions.
摘要翻译： 本发明涉及与选自阿尔法中选择的环糊精Silybinin的新颖包合物 - ，β - 和γ-环糊精和一种适宜的衍生物和其制备方法。 Silybinin的新颖包合物显示出相比于Silybinin高度改善的生物利用率，这使得它们在各种肝毒性病症的治疗特别有趣。
-
3.发明授权Inclusion complexes with silybinin, their preparation and pharmaceutical compositions containing them 失效包合配合物与Silybinin，其制备方法和含有这些药物制剂
公开(公告)号：EP0422497B1
公开(公告)日：1996-03-06
申请号：EP90118964.7
申请日：1990-10-04
发明人： Valcavi, Umberto, Prof. , Monterosso, Vincenzo, Dr. , Caponi, Roberto, Dr. , Bosone, Enrico, Dr. , Wachter, Wilfried Peter, Dr. rer. nat. , Szejtli, Jozsef, Prof. Dr.
IPC分类号： C08B37/16 , A61K31/735
CPC分类号： C08B37/0015
-
-
搜索结果
3 条记录 (耗时 0.011 秒)
