专利检索 ap:("ID Pharma Co., Ltd.") AND inv:"FUSAKI, Noemi" 第 1 页

1.

发明授权
COMPOSITION FOR INDUCING PLURIPOTENT STEM CELL, AND USE THEREOF 有权
标题翻译：用于诱导多功能干细胞的组合物及其用途

公开(公告)号：EP2612911B1

公开(公告)日：2018-01-17

申请号：EP11821786.8

申请日：2011-08-30

申请人： ID Pharma Co., Ltd.

发明人： BAN, Hiroshi , UEDA, Yasuji , FUSAKI, Noemi , SAEKI, Koichi , HASEGAWA, Mamoru

IPC分类号： C12N15/09 , C12N5/10 , C12N7/00 , C12N15/86

CPC分类号： C12N15/86 , C12N5/0696 , C12N15/63 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2506/13 , C12N2510/00 , C12N2760/18843

摘要： The present invention provides Sendai virus vectors in which genes that encode reprograming factors for inducing pluripotent stem cells are incorporated in a specific order, compositions comprising these vectors for gene delivery to be used in the induction of pluripotent stem cells, and uses thereof. Incorporation of the KLF gene, OCT gene, and SOX gene in a specific order into a single Sendai virus vector successfully and significantly increased the efficiency of pluripotent stem cell induction. Loading multiple reprogramming factors into a single vector can further increase the induction efficiency of pluripotent stem cells while reducing the number of necessary vectors.

2.

发明授权
METHOD FOR PRODUCTION OF REPROGRAMMED CELL USING CHROMOSOMALLY UNINTEGRATED VIRUS VECTOR 有权
标题翻译：使用染色体未整合的病毒载体产生重编程细胞的方法

公开(公告)号：EP2322611B1

公开(公告)日：2016-06-01

申请号：EP09797978.5

申请日：2009-07-16

申请人： ID Pharma Co., Ltd.

发明人： FUSAKI, Noemi , BAN, Hiroshi , HASEGAWA, Mamoru , YONEMITSU, Yoshikazu

IPC分类号： C07K14/47 , C12N5/074

CPC分类号： C12N15/86 , C07K14/4702 , C12N5/0696 , C12N7/00 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2510/00 , C12N2760/18622 , C12N2760/18643 , C12N2760/18645 , C12N2760/18662 , C12N2760/18822 , C12N2760/18843