公开(公告)号：EP3826656A1

公开(公告)日：2021-06-02

申请号：EP19752560.3

申请日：2019-07-23

申请人： Indena S.p.A.

发明人： ARPINI, Sabrina ,  MOMBELLI, Giacomo ,  MORAZZONI, Paolo ,  PETERLONGO, Federico ,  RIVA, Antonella ,  RONCHI, Massimo

IPC分类号： A61K36/45 ,  A61P31/00

公开(公告)号：EP3280407A1

公开(公告)日：2018-02-14

申请号：EP16716505.9

申请日：2016-03-30

申请人： Indena S.p.A.

发明人： MORAZZONI, Paolo ,  IORI, Renato

IPC分类号： A61K31/26 ,  A61K31/7024 ,  A61K36/31 ,  A61P25/02

摘要： The present invention relates to the use of glucomoringin (GMG) and of the corresponding isothiocyanate derivative glucomoringin des-thioglucoside (GMG-ITC) as modulators of peripheral pain with specific reference to that linked with diabetic peripheral neuropathy and chemotherapy-induced neuropathy.

公开(公告)号：EP3010879A1

公开(公告)日：2016-04-27

申请号：EP14735872.5

申请日：2014-06-17

申请人： Indena S.p.A.

发明人： MORAZZONI, Paolo ,  RIVA, Antonella ,  FONTANA, Gabriele

IPC分类号： C07C45/67 ,  C07C49/757 ,  A61K31/122 ,  A61P25/28

CPC分类号： C07C49/757 ,  C07C45/673 ,  C07C2602/46

摘要： Disclosed is a compound having the formula a) or b); a: R = CH
3 ; b: R = CH
2 CH
3 , and its use in the prevention and/or treatment of Alzheimer's disease.

摘要翻译： 公开了具有式a）或b）的化合物; a：R = CH3; b：R = CH2CH3，以及其在预防和/或治疗阿尔茨海默病中的用途。

公开(公告)号：EP1497250B1

公开(公告)日：2008-08-13

申请号：EP03718778.8

申请日：2003-04-18

申请人： INDENA S.p.A.

发明人： BOMBARDELLI, Ezio ,  MORAZZONI, Paolo ,  RIVA, Antonella ,  FUZZATI, Nicola

IPC分类号： C07C49/733 ,  C07C49/743 ,  C07C69/013 ,  A61K31/122 ,  A61K31/215 ,  A61P25/28

CPC分类号： C07C69/013 ,  C07C45/62 ,  C07C45/64 ,  C07C45/78 ,  C07C49/733 ,  C07C49/743 ,  C07C2602/46

摘要： The use of the reduction products of hyperforin and adhyperforin, pharmaceutically acceptable salts or esters thereof, in the pharmaceutical and/or nutritional field, in particular in the treatment of depression and Alzheimer's disease.

公开(公告)号：EP1605957B1

公开(公告)日：2008-04-09

申请号：EP04708771.3

申请日：2004-02-06

申请人： INDENA S.p.A.

发明人： MORAZZONI, Paolo ,  DURANTI, Marcello

IPC分类号： A61K36/48 ,  A61P3/10

CPC分类号： A61K38/168 ,  A61K36/23 ,  A61K36/48

摘要： The present invention discloses the use of lupin conglutin gamma or of proteins showing homology higher than 50% with lupin conglutin gamma, for the preparation of a medicament, food supplements or foods for the treatment of type II diabetes, pharmaceutical and nutritional compositions containing lupin conglutin gamma, and the use of lupin conglutin gamma as therapeutical agent, in particular as hypoglycemizing agent. Lupin conglutin gamma may be used in pure form or in form of extracts, mixtures or concentrates.

公开(公告)号：EP1539203B1

公开(公告)日：2007-09-26

申请号：EP03783996.6

申请日：2003-06-30

申请人： INDENA S.p.A.

发明人： GIORI, Andrea ,  ANELLI, Alessandro ,  MORAZZONI, Paolo ,  DI PIERRO, Francesco

IPC分类号： A61K36/28

CPC分类号： A61K36/28

摘要： An Echinacea angustifolia extract and a process for the preparation thereof are herein described. The extract is characterized by an alkylamides content lower than 0.1 %, an echinacoside content ranging from 1 to 10% and containing from 1 to 15% of a polysaccharide characteristic of Echinacea angustifolia. The extract can be used for the treatment of pathological conditions in which it is desirable to strengthen the immune defenses.

公开(公告)号：EP1469741B1

公开(公告)日：2006-10-11

申请号：EP03706387.2

申请日：2003-01-27

申请人： INDENA S.p.A.

发明人： DURANTI, Marcello ,  MORAZZONI, Paolo

IPC分类号： A23J3/16 ,  A23J1/14 ,  A23L1/305

CPC分类号： A61K38/168 ,  A23J1/14 ,  A23J3/16 ,  A23L33/185 ,  Y02E50/17

摘要： A process for the extraction, purification and enzymatic modification of beta-conglycinin alpha' subunit, wherein beta-conglycinin is selectively extracted from ground, deffated soy, then precipitated by treatment with aqueous ethanol the enriched fraction is then subjected to Metal Affinity Chromatography MAC in denaturant conditions to obtain the alpha' subunit, which is treated with chymotrypsin, then subjected to a further MAC to recover the amino-terminal region of this polypeptide MW 28,000 Da.

公开(公告)号：EP1140115A2

公开(公告)日：2001-10-10

申请号：EP99966956.7

申请日：1999-12-13

申请人： INDENA S.p.A.

发明人： BOMBARDELLI, Ezio ,  MORAZZONI, Paolo

IPC分类号： A61K31/685 ,  A61K31/353 ,  A61P3/06 ,  A61P9/10 ,  A61K31/66 ,  A61K31/35

CPC分类号： A61K47/544

摘要： The phospholipid complexes of proanthocyanidin A2 are useful for the prevention and the treatment of pathological conditions on atherosclerotic base.

公开(公告)号：EP2627345B1

公开(公告)日：2014-07-23

申请号：EP11778814.1

申请日：2011-10-05

申请人： Indena S.p.A.

发明人： BOMBARDELLI, Ezio ,  RONCHI, Massimo ,  MORAZZONI, Paolo

IPC分类号： A61K36/45 ,  A61K36/185 ,  A61K36/28 ,  A61P1/02 ,  A61P11/00 ,  A61P31/16

CPC分类号： A61K36/00 ,  A61K36/185 ,  A61K36/28 ,  A61K36/45 ,  A61K2300/00

公开(公告)号：EP2627345A1

公开(公告)日：2013-08-21

申请号：EP11778814.1

申请日：2011-10-05

申请人： Indena S.p.A.

发明人： BOMBARDELLI, Ezio ,  RONCHI, Massimo ,  MORAZZONI, Paolo

IPC分类号： A61K36/185 ,  A61K36/28 ,  A61K36/45

CPC分类号： A61K36/00 ,  A61K36/185 ,  A61K36/28 ,  A61K36/45 ,  A61K2300/00

摘要： The present invention relates to formulations containing extracts of
Vaccinium myrtillus or other species rich in anthocyanosides,
Punica
granatum, Echinacea , and optionally
Krameria triandra . Said formulations are useful in the treatment of disorders of the mouth and its adnexa, the throat and respiratory tract, and in the treatment of influenza.