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公开(公告)号:EP4440644A2
公开(公告)日:2024-10-09
申请号:EP22830701.3
申请日:2022-12-02
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Paris Cité , Université Paris XIII Paris-Nord
发明人: CALIGIURI, Giuseppina , NICOLETTI, Antonino , SKARBEK, Charles , BIANCHI, Elisabetta , INGENITO, Raffaele
IPC分类号: A61L31/00 , A61K38/00 , A61P9/10 , C07K14/705
CPC分类号: A61K38/00 , A61P9/10 , C07K14/705 , A61L31/10 , A61L27/54 , A61L31/16 , A61L27/34 , A61L2300/2520130101
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公开(公告)号:EP4440643A2
公开(公告)日:2024-10-09
申请号:EP22829836.0
申请日:2022-12-02
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Paris Cité , Université Paris XIII Paris-Nord , Alchimedics
发明人: CALIGIURI, Giuseppina , NICOLETTI, Antonino , SKARBEK, Charles , LEFEVRE, Isabelle , BUREAU, Christophe
IPC分类号: A61L31/00 , A61K38/00 , A61P9/10 , C07K14/705
CPC分类号: A61K38/00 , A61P9/10 , C07K14/705 , A61L31/10 , A61L27/54 , A61L31/16 , A61L27/34 , A61L2300/2520130101
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公开(公告)号:EP4227684A1
公开(公告)日:2023-08-16
申请号:EP22305149.1
申请日:2022-02-10
申请人: Tridek-One Therapeutics , INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Paris XIII
IPC分类号: G01N33/569 , G01N33/68
摘要: The present invention relates to in vitro assay for inducing neutrophil extracellular trap (NET) formation, comprising contacting neutrophils in in vitro culture with immobilized human polyvalent immunoglobulins; and to uses thereof, in particular in an in vitro method for screening a drug for its ability to modulate NET formation, in an in vitro method for assessing the susceptibility of a subject to NET formation, in an in vitro method for predicting the response of a subject to a modulator of NET formation, and in in vitro method for monitoring the response of a subject to an immunomodulator.
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公开(公告)号:EP3452109A1
公开(公告)日:2019-03-13
申请号:EP17719860.3
申请日:2017-05-03
申请人: Institut National de la Santé et de la Recherche Médicale (INSERM) , Université Paris Diderot - Paris 7 , Université Paris XIII Paris-Nord , Assistance Publique - Hôpitaux de Paris , Institut Pasteur , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人: BAY, Sylvie , NICOLETTI, Antonino , LE GULUDEC, Dominique , VIGNE, Jonathan , CALIGIURI, Giuseppina
IPC分类号: A61K51/08 , A61K103/10 , G01N33/60 , C07K7/06 , A61P29/00
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公开(公告)号:EP4157282A1
公开(公告)日:2023-04-05
申请号:EP21729302.6
申请日:2021-05-27
申请人: Institut National de la Santé et de la Recherche Médicale (INSERM) , Université Paris Cité , Kapto Medical SAS , UNIVERSITE PARIS 13 PARIS NORD
IPC分类号: A61K31/5415 , A61K31/34 , A61K45/00 , A61P7/02
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