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公开(公告)号:EP3277841A1
公开(公告)日:2018-02-07
申请号:EP16723255.2
申请日:2016-03-30
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , Institut Jean Paoli & Irène Calmettes , Université d'Aix Marseille , Centre National de la Recherche Scientifique (CNRS)
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , G01N33/57426 , G01N33/57492 , G01N2400/00 , G01N2800/52
摘要: The present invention relates to a method for predicting the survival time of a patient suffering from acute myeloid leukemia (AML) comprising i) determining the frequency of JAM-C expressing LSCs in a sample obtained from the patient ii) comparing the frequency determined at step i) with its predetermined reference value and iii) providing a good prognosis when the frequency determined at step i) is lower than its predetermined reference value, or 10 providing a bad prognosis when the frequency determined at step i) is higher than its predetermined reference value.