公开(公告)号：EP3359554A1

公开(公告)日：2018-08-15

申请号：EP16778419.8

申请日：2016-10-10

申请人： INSTITUT EUROPEEN DE BIOLOGIE CELLULAIRE ,  Centre de Recherches Biologiques et d'Expérimentations Cutanées ,  Centre National de la Recherche Scientifique (CNRS)

发明人： HOCQUAUX, Michel ,  ALMEIDA ÉPOUSE SCALVINO, Stéphanie ,  LATI, Elian ,  BAKALA, Joanna

IPC分类号： C07K7/06 ,  C07K5/11 ,  C07K5/09 ,  A61K38/00

CPC分类号： C07K7/06 ,  A61K8/64 ,  A61K38/00 ,  A61K38/06 ,  A61K38/07 ,  A61K38/08 ,  A61Q7/00 ,  C07K5/0817 ,  C07K5/1019

摘要： The subject matter of the present invention concerns a novel family of peptide conjugates of formula (I): A-X1-X2-Pro-Ala-X-B in which: - A is a hydrogen atom, a C6 to C20 acyl group or a cholesterol residue; - X1 is a covalent bond, an alanine or a proline; - X2 is an arginine, a lysine or an alanine; - X is a lysine, an alanine or a phenylalanine; and - B is a hydroxyl or an amine; or one of the salts thereof, which are preferentially pharmaceutically, dermatologically or cosmetically acceptable, and also the processes for the synthesis thereof, and the uses thereof for reducing hair loss and stimulating hair growth.