公开(公告)号：EP1128902A1

公开(公告)日：2001-09-05

申请号：EP99971737.4

申请日：1999-10-26

申请人： INSTITUT FÜR PHYSIKALISCHE HOCHTECHNOLOGIE E.V. ,  Microdrop GmbH

发明人： DÖRING, Michael ,  MAYER, Günter ,  SCHLINGLOFF, Gregor ,  SCHOBER, Andreas

IPC分类号： B01J19/00 ,  G01N35/02

CPC分类号： G01N35/10 ,  B01J19/0046 ,  B01J2219/00315 ,  B01J2219/00459 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00648 ,  B01J2219/00659 ,  C40B60/14 ,  G01N2035/00564 ,  G01N2035/00574

摘要： The invention relates to a sample sorting, conveying and receiving device for small microspheres. Said device is provided with a first module which contains at least one microsphere receiving zone (12). Said microsphere receiving zone (12) is provided with a plurality of microsphere receiving subzones (121) subject to the geometrical characteristics of a detachable sample receiving carrier (2) with respect to number, location and dimensions of individual sample chambers (21). Said microsphere receiving subzones are arranged in such a manner that their center lines (X-X) correspond to the center lines (Y-Y) of the individual sample chambers (21) of the sample receiving carrier (2) which chambers are to be filled or evacuated. Every microsphere receiving subzone (121) has a recess (122) for receiving a microsphere (3). Said recess has a depth (t) which is chosen such that once the microsphere (3)s received, it is substantially flush with a first surface (123) of the microsphere receiving zone (12). Every recess (122) has an opening (125) in its bottom area, which opening has a diameter that is smaller than the diameter of the microsphere (3). Said opening (125) is followed by a gap (126) which extends in the direction of the second surface (124) of the microsphere receiving zone (12). These gaps can be impinged upon by a negative pressure or overpressure via one or more channels or via an interlinked chamber of the first module.

公开(公告)号：EP0706646B1

公开(公告)日：1998-03-25

申请号：EP94922254.1

申请日：1994-07-02

申请人： INSTITUT FÜR MOLEKULARE BIOLOGIE E.V. ,  INSTITUT FÜR PHYSIKALISCHE HOCHTECHNOLOGIE E.V. ,  Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin

发明人： EIGEN, Manfred ,  HENCO, Karsten ,  SCHOBER, Andreas ,  SCHWIENHORST, Andreas ,  KÖHLER, Michael ,  THÜRK, Marcel ,  GÜNTHER, Rolf ,  DÖRING, Michael

IPC分类号： G01N1/28 ,  B01L3/00 ,  B01J19/00 ,  G01N30/00 ,  C12Q1/68

CPC分类号： B01L3/50255 ,  B01J19/0046 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/00319 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/005 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00704 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01L3/5085 ,  C40B40/06 ,  C40B40/10 ,  G01N1/28 ,  G01N30/24 ,  G01N30/466 ,  G01N30/6095 ,  G01N30/74 ,  G01N2030/8813 ,  G01N2030/8827 ,  G01N2030/8831 ,  G01N2035/00237

摘要： Described is a device designed to hold a multiplicity of chemical and/or biological samples. The device has at least one mechanical micro-sample holder (50) with a lower surface (60) and, remote from it, an upper surface (58), the holder being divided into a multiplicity of recesses (52) with floors, the recesses (52) being produced using non-cutting techniques, in particular by etching. In order to produce apertures extending between the upper and lower surfaces of the sample holder, at least part of the floor (54) of each recess (52) is porous.