专利检索 ap:("INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)") AND inv:"FACCHINETTI, Patricia" 第 1 页

1.

发明公开
NOUVELLE METALLOPROTEASE MEMBRANAIRE NEP II ET SON UTILISATION POUR LE CRIBLAGE D'INHIBITEURS UTILES EN THERAPIE 审中-公开
标题翻译： REED金属蛋白酶NEP II及其用途中的一种检查方法与INHIBITIOREN的NACHWEISS治疗作用

公开(公告)号：EP1068336A2

公开(公告)日：2001-01-17

申请号：EP99911898.7

申请日：1999-04-07

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

发明人： OUIMET, Tanja , GROS, Claude , ROSE, Christiane , BONHOMME, Marie-Chantal , FACCHINETTI, Patricia , SCHWARTZ, Jean-Charles

IPC分类号： C12N15/57 , C12N9/64 , C12N5/10 , C07K16/40 , G01N33/573 , C12Q1/68 , C12Q1/37

CPC分类号： C12N9/6489

摘要： The invention concerns an isolated polypeptide comprising an amino acid sequence selected among the sequence SEQ ID n° 2 or n° 4, a sequence derived from or homologous with said sequence SEQ ID n° 2 or n° 4, or a biologically active fragment of said sequence SEQ ID n° 2 or n° 4, said isolated polypeptide being designated as 'NEP II', and the use of said NEP II polypeptide for screening inhibitors useful in therapy.