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1.发明授权UTILISATION DES PROTEINES ET DES PEPTIDES CODES PAR LE GENOME D'UNE NOUVELLE SOUCHE DE CORONAVIRUS ASSOCIE AU SRAS 有权蛋白质和肽的使用编码的基因组中的新与相关SARS冠状病毒株
公开(公告)号：EP1697507B1
公开(公告)日：2012-09-19
申请号：EP04805624.6
申请日：2004-12-02
发明人： VAN DER WERF, Sylvie , ESCRIOU, Nicolas , CRESCENZO-CHAIGNE, Bernadette , MANUGUERRA, Jean-Claude , KUNST, Frederik, Institut Pasteur , CALLENDRET, Benoît , BETTON, Jean-Michel , LORIN, Valérie , GERBAUD, Sylvie , BURGUIERE, Ana Maria , AZEBI, Saliha , CHARNEAU, Pierre , TANGY, Frédéric , COMBREDET, Chantal , DELAGNEAU, Jean-François , MARTIN, Monique
IPC分类号： C12N7/00 , C07K14/165 , G01N33/569
CPC分类号： C07K14/005 , C12N7/00 , C12N2770/20022 , G01N33/569
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2.发明授权DENGUE AND WEST NILE VIRUS PROTEINS AND GENES AND THEIR THERAPEUTIC APPLICATION 有权蛋白及基因来自新登革热和西尼罗河病毒和治疗用途
公开(公告)号：EP1599495B9
公开(公告)日：2013-11-13
申请号：EP04714865.5
申请日：2004-02-26
CPC分类号： A61K39/12 , A61K38/00 , A61K39/00 , A61K2039/5256 , A61K2039/53 , C07K14/005 , C07K14/1825 , C12N15/86 , C12N2760/18443 , C12N2770/24122 , C12Q1/701 , Y02A50/386 , Y02A50/394 , Y02A50/53
摘要： The present invention relates to the development of viral vectors expressing different immunogens from the West Nile Encephalitis Virus (WNV) or the Dengue virus which are able to induce protective humoral and cellular immune responses against WNV or Dengue virus infections. More specifically, the present invention relates to three (3) antigens from WNV (the secreted envelope glycoprotein (E), the heterodimer glycoproteins (pre-M-E) and the NSI protein) and from Dengue virus (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre- m-e) and the nsl protein) and their use in vaccinal, therapeutic and diagnostic applications.
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3.发明授权DENGUE AND WEST NILE VIRUS PROTEINS AND GENES AND THEIR THERAPEUTIC APPLICATION 有权蛋白及基因来自新登革热和西尼罗河病毒和治疗用途
公开(公告)号：EP1599495B1
公开(公告)日：2012-08-29
申请号：EP04714865.5
申请日：2004-02-26
CPC分类号： A61K39/12 , A61K38/00 , A61K39/00 , A61K2039/5256 , A61K2039/53 , C07K14/005 , C07K14/1825 , C12N15/86 , C12N2760/18443 , C12N2770/24122 , C12Q1/701 , Y02A50/386 , Y02A50/394 , Y02A50/53
摘要： The present invention relates to the development of viral vectors expressing different immunogens from the West Nile Encephalitis Virus (WNV) or the Dengue virus which are able to induce protective humoral and cellular immune responses against WNV or Dengue virus infections. More specifically, the present invention relates to three (3) antigens from WNV (the secreted envelope glycoprotein (E), the heterodimer glycoproteins (pre-M-E) and the NSI protein) and from Dengue virus (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre- m-e) and the nsl protein) and their use in vaccinal, therapeutic and diagnostic applications.
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4.发明授权
公开(公告)号：EP1694829B1
公开(公告)日：2010-08-04
申请号：EP04805625.3
申请日：2004-12-02
发明人： VAN DER WERF, Sylvie , ESCRIOU, Nicolas , CRESCENZO-CHAIGNE, Bernadette , MANUGUERRA, Jean-Claude , KUNST, Frederik, Inst. Pasteur Bureau des Brevets et Inventions , CALLENDRET, Benoît , BETTON, Jean-Michel , LORIN, Valérie , GERBAUD, Sylvie , BURGUIERE, Ana Maria , AZEBI, Saliha , CHARNEAU, Pierre , TANGY, Frédéric , COMBREDET, Chantal , DELAGNEAU, Jean-François , MARTIN, Monique
IPC分类号： C12N7/00
CPC分类号： C07K14/005 , C12N7/00 , C12N2770/20022 , G01N33/569
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5.发明公开UTILISATION DES PROTEINES ET DES PEPTIDES CODES PAR LE GENOME D'UNE NOUVELLE SOUCHE DE CORONAVIRUS ASSOCIE AU SRAS 有权蛋白质和肽的使用编码的基因组中的新与相关SARS冠状病毒株
公开(公告)号：EP1697507A1
公开(公告)日：2006-09-06
申请号：EP04805624.6
申请日：2004-12-02
发明人： VAN DER WERF, Sylvie , ESCRIOU, Nicolas , CRESCENZO-CHAIGNE, Bernadette , MANUGUERRA, Jean-Claude , KUNST, Frederik, Institut Pasteur , CALLENDRET, Benoît , BETTON, Jean-Michel , LORIN, Valérie , GERBAUD, Sylvie , BURGUIERE, Ana Maria , AZEBI, Saliha , CHARNEAU, Pierre , TANGY, Frédéric , COMBREDET, Chantal , DELAGNEAU, Jean-François , MARTIN, Monique
IPC分类号： C12N7/00 , C07K14/165 , G01N33/569
CPC分类号： C07K14/005 , C12N7/00 , C12N2770/20022 , G01N33/569
摘要： The invention relates to the use of proteins and peptides coded by the genome of the isolated or purified strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from sample reference number 031589 and, in particular, to the use of protein S and the derivative antibodies thereof as diagnostic reagents and as a vaccine.
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6.发明公开
公开(公告)号：EP1694829A2
公开(公告)日：2006-08-30
申请号：EP04805625.3
申请日：2004-12-02
发明人： VAN DER WERF, Sylvie , ESCRIOU, Nicolas , CRESCENZO-CHAIGNE, Bernadette , MANUGUERRA, Jean-Claude , KUNST, Franck, Institut Pasteur Bureau des Brevets , CALLENDRET, Benoît , BETTON, Jean-Michel , LORIN, Valérie , GERBAUD, Sylvie , BURGUIERE, Ana Maria , AZEBI, Saliha , CHARNEAU, Pierre , TANGY, Frédéric , COMBREDET, Chantal , DELAGNEAU, Jean-François , MARTIN, Monique
IPC分类号： C12N7/00
CPC分类号： C07K14/005 , C12N7/00 , C12N2770/20022 , G01N33/569
摘要： The invention relates to a novel strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from a sample collected in Hanoi (Vietnam), reference number 031589, nucleic acid molecules originating from the genome of same, proteins and peptides coded by said nucleic acid molecules and, more specifically, protein N and the applications thereof, for example, as diagnostic reagents and/or as a vaccine.
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7.发明公开
公开(公告)号：EP1599495A2
公开(公告)日：2005-11-30
申请号：EP04714865.5
申请日：2004-02-26
IPC分类号： C07K14/18
CPC分类号： A61K39/12 , A61K38/00 , A61K39/00 , A61K2039/5256 , A61K2039/53 , C07K14/005 , C07K14/1825 , C12N15/86 , C12N2760/18443 , C12N2770/24122 , C12Q1/701 , Y02A50/386 , Y02A50/394 , Y02A50/53
摘要： The present invention relates to the development of viral vectors expressing different immunogens from the West Nile Encephalitis Virus (WNV) or the Dengue virus which are able to induce protective humoral and cellular immune responses against WNV or Dengue virus infections. More specifically, the present invention relates to three (3) antigens from WNV (the secreted envelope glycoprotein (E), the heterodimer glycoproteins (pre-M-E) and the NSI protein) and from Dengue virus (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre- m-e) and the nsl protein) and their use in vaccinal, therapeutic and diagnostic applications.
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8.发明公开USE OF A GENETICALLY MODIFIED INFECTIOUS MEASLES VIRUS WITH ENHANCED PRO-APOPTOTIC PROPERTIES (MV-DELTAC VIRUS) IN CANCER THERAPY 审中-公开遗传修饰的感染性麻疹病毒晚期使用的功能促凋亡（MV-Δ肝炎病毒）的癌症治疗
公开(公告)号：EP2948157A1
公开(公告)日：2015-12-02
申请号：EP14701698.4
申请日：2014-01-20
申请人： Institut Pasteur , Centre National de la Recherche Scientifique (CNRS) , Institut National de la Santé et de la Recherche Médicale , Université de Nantes
发明人： TANGY, Frédéric , GREGOIRE, Marc , FONTENEAU, Jean-François , GUILLERME, Jean-Baptiste , COMBREDET, Chantal
CPC分类号： A61K39/165 , A61K35/15 , A61K35/768 , A61K2039/5154 , A61K2039/5254 , C12N7/00 , C12N2760/18421 , C12N2760/18432 , C12N2760/18434 , C12N2760/18462
摘要： The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.
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9.发明公开
公开(公告)号：EP3474892A1
公开(公告)日：2019-05-01
申请号：EP17752483.2
申请日：2017-06-23
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10.发明授权POLYPEPTIDES CHIMERIQUES ET LEURS APPLICATIONS THÉRAPEUTIQUES CONTRE UNE INFECTION À FLAVIVIRIDAE 有权CHIMÄRISCHEPOLYPEPTIDE UND IHRE THERAPEUTISCHE VERWENDUNG GEGEN FLAVIVIRIDAE-INFEKTIONEN
公开(公告)号：EP1893228B1
公开(公告)日：2016-03-23
申请号：EP06778626.9
申请日：2006-06-20
发明人： TANGY, Frédéric , LUCAS-HOURANI, Marianne , NAVARRO-SANCHEZ, Erika , FRENKIEL, Marie-Pascale , BEDOUELLE, Hugues , COMBREDET, Chantal , DESPRES, Philippe
CPC分类号： C07K14/005 , A61K38/00 , A61K39/12 , A61K39/165 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/55 , A61K2039/55505 , C07K2319/00 , C07K2319/04 , C12N7/00 , C12N15/86 , C12N2760/18434 , C12N2760/18443 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/386 , Y02A50/388 , Y02A50/39 , Y02A50/394
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