专利检索 ap:("IRM LLC") AND inv:"CHE, Jianwei" 第 1 页

1.

发明公开
COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS 审中-公开
标题翻译：化合物和组合物SYK激酶抑制剂

公开(公告)号：EP2459558A2

公开(公告)日：2012-06-06

申请号：EP10747541.0

申请日：2010-07-30

申请人： IRM LLC

发明人： CHE, Jianwei , DING, Qiang , HE, Xiaohui , LIU, Hong , LIU, Yahua , MICHELLYS, Pierre-Yves , OKRAM, Barun , WU, Xu , YANG, Kunyong , ZHU, Xuefeng

IPC分类号： C07D471/04

CPC分类号： C07D471/04

摘要： Provided herein area novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated Syk kinase activity.

2.

发明公开
PYRIDO [4, 3-D]PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS 审中-公开
标题翻译：吡啶并[4,3-D]吡啶并吡啶盐酸盐KINASEINHIBITOREN

公开(公告)号：EP2250169A1

公开(公告)日：2010-11-17

申请号：EP09708389.3

申请日：2009-01-27

申请人： IRM LLC

发明人： DING, Qiang , LIU, Yahua , WU, Xu , JIN, Qihui , CHE, Jianwei , YAN, S. Frank

IPC分类号： C07D471/04 , A61K31/519

CPC分类号： C07D471/04

摘要： The invention provides a class of compounds of Formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Syk, ZAP70, KDR, FMS, FLT3, c-Kit, RET, TrkA, TrkB, TrkC, IGR-IR, AIk, c-FMS, or combinations thereof.

3.

发明公开
2, 7 -NAPHTHYRIDIN- 1 -ONE DERIVATIVES AS SYK KINASE INHIBITORS 审中-公开
标题翻译： 2,7 - 萘啶-1-酮衍生物AS SYK激酶抑制剂

公开(公告)号：EP2459556A1

公开(公告)日：2012-06-06

申请号：EP10737729.3

申请日：2010-07-27

申请人： IRM LLC

发明人： CHE, Jianwei , CHEN, Bei , DING, Qiang , HAO, Xueshi , HE, Xiaohui , JIANG, Songchun , JIN, Qihui , JIN, Yunho , LIU, Hong , LIU, Yahua , OKRAM, Barun , UNO, Tetsuo , WU, Xu , YANG, Kunyong , ZHU, Xuefeng

IPC分类号： C07D471/04 , A61K31/4375 , A61P11/00 , A61P29/00 , A61P35/00 , A61P37/00

CPC分类号： C07D471/04 , A61K31/4375

摘要： Provided herein area novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated Syk kinase activity.

4.

发明公开
COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS 审中-公开
标题翻译：化合物和组合物作为激酶抑制剂

公开(公告)号：EP2238137A1

公开(公告)日：2010-10-13

申请号：EP09705446.4

申请日：2009-01-27

申请人： IRM LLC

发明人： OKRAM, Barun , UNO, Tetsuo , DING, Qiang , LIU, Yahua , JIN, Yunho , JIN, Qihui , WU, Xu , CHE, Jianwei , YAN, S. Frank , HAO, Xueshi

IPC分类号： C07D471/04 , A61K31/4375

CPC分类号： C07D471/04

摘要： The invention provides a novel class of 2,7-naphthyridin derivatives; pharmaceutical compositions comprising such compounds and methods of using such compounds to treat o prevent diseases or disorders associated with abnormal or deregulated kinase activity,particulary Syk,ZAP70,KDR,FMS,FLT*,c-Kit,RET,TrkA,TrkB,TrkC-GR-1R,Alk,c- FMS.or combinations thereof.