专利检索 ap:("IRM LLC") AND inv:"SMITH, Jeffrey M." 第 1 页

1.

发明公开
COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS 有权
标题翻译：化合物和组合物作为激酶抑制剂TRK

公开(公告)号：EP2678338A1

公开(公告)日：2014-01-01

申请号：EP12708450.7

申请日：2012-02-23

申请人： IRM LLC

发明人： MOLTENI, Valentina , FAN, Yi , LOREN, Jon , SMITH, Jeffrey M. , FLATT, Brenton T.

IPC分类号： C07D471/04

CPC分类号： C07D471/04 , C07D207/09

摘要： The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity.

2.

发明公开
IMIDAZO [1, 2]PYRIDAZIN COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS 审中-公开
标题翻译：咪唑并[1,2]哒嗪化合物和组合物AS TRK抑制剂

公开(公告)号：EP2614062A1

公开(公告)日：2013-07-17

申请号：EP11758063.9

申请日：2011-09-09

申请人： IRM LLC

发明人： FAN, Yi , LOREN, Jon , MOLTENI, Valentina , ALBAUGH, Pamela A. , CHOPIUK, Gregory , SMITH, Jeffrey M. , FLATT, Brenton T.

IPC分类号： C07D471/04 , C07D487/04 , A61K31/4353 , A61K31/4985 , A61P37/00

CPC分类号： C07D471/04 , C07D487/04

摘要： The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity.