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公开(公告)号:EP3227276A1
公开(公告)日:2017-10-11
申请号:EP15865371.7
申请日:2015-11-30
申请人: Ignyta, Inc.
发明人: HORNBY, Zachary Dolph , LI, Gang , ANDERSON, David Wesley , BRODEUR, Garrett M. , IYER, Radhika
IPC分类号: C07D403/12 , C07D231/56 , A61K31/496
CPC分类号: A61K31/496 , A61K31/4188 , A61K31/4745 , A61K31/495 , A61K45/06 , C07D231/56 , C07D403/12 , C07D405/12 , A61K2300/00
摘要: Disclosed are methods of treating neuroblastoma in a cancer patient by administration of a Trk inhibitor in combination with one more chemotherapeutic agents. Also disclosed are pharmaceutical compositions comprising a Trk inhibitor and one or more chemotherapeutic agents.
摘要翻译: 公开了通过与另一种化学治疗剂组合施用Trk抑制剂来治疗癌症患者中的神经母细胞瘤的方法。 还公开了包含Trk抑制剂和一种或多种化学治疗剂的药物组合物。