公开(公告)号：EP1261326A1

公开(公告)日：2002-12-04

申请号：EP01914781.8

申请日：2001-03-07

申请人： Ilex Oncology, Inc.

发明人： LEVENSON, Corey ,  SHAKED, Ze'ev

IPC分类号： A61K31/00

CPC分类号： A61K31/195 ,  Y10S977/773 ,  Y10S977/775 ,  Y10S977/905 ,  Y10S977/907

摘要： The present invention concerns a method for preventing and/or treating cancer in a patient comprising administering an effective amount of substantially purified D enantiomer of difluoromethylornithine (D-DFMO) or an analog of D-DFMO to the patient. D-DFMO or an analog thereof is administered at a dose of about 0.05 to about 20.0 gm/M2/day. D-DFMO or an analog thereof may be administered more than once for the treatment and/or prevention of cancer. Methods of administration as well as compositions and formulations of substantially purified D-DFMO and analogs of D-DFMO are described.