公开(公告)号：EP3839032A1

公开(公告)日：2021-06-23

申请号：EP19218559.3

申请日：2019-12-20

申请人： Imec VZW ,  Katholieke Universiteit Leuven, K.U.Leuven R&D

发明人： DELAHANTY, Aaron ,  BRAEKEN, Dries ,  ANDREI, Alexandru ,  PEUMANS, Peter ,  MORA LOPEZ, Carolina ,  REUMERS, Veerle ,  ROCHUS, Veronique ,  WEEKERS, Bart

IPC分类号： C12M1/12 ,  C12M1/42 ,  C12M1/00

摘要： A semiconductor cell culture device for three-dimensional cell culture comprises: a semiconductor material layer (102) in which a cell culture portion (110) of semiconductor material is defined, wherein the cell culture portion (110) defines an area within the semiconductor material layer (102) surrounded by semiconductor material, wherein the cell culture portion (110) comprises a mesh structure (112) having island structures (116) being interconnected by bridge structures (118) and defining through-pores (114) between the island structures (116) allowing for selective transport of cell constructs, cellular components, proteins or other large molecules through the semiconductor material layer (102) and on opposite sides of the cell culture portion (110) in the semiconductor material layer (102), and a supporting structure (120) connected to the cell culture portion (110).