公开(公告)号：EP1299113A2

公开(公告)日：2003-04-09

申请号：EP01965092.8

申请日：2001-07-09

申请人： Immatics Biotechnologies GmbH

发明人： Singh-Jasuja, Harpreet ,  Schild, Hansjörg

IPC分类号： A61K38/17 ,  C12N5/08 ,  A61K39/00 ,  A61P35/00

CPC分类号： A61K38/1709 ,  Y02A50/473

摘要： The invention relates to the use of gp96 molecules that carry no antigens of interest, for marking and/or activating antigen-presenting cells (APCs), for example dendritic cells, monocytes, macrophages, B cells and peritoneal exudation cells. Said APCs can be loaded with antigens once they have been activated and are used to induce an immune response, or in tumor therapy.