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公开(公告)号：EP3380510A1
公开(公告)日：2018-10-03
申请号：EP16805182.9
申请日：2016-11-23
IPC分类号： C07K14/705 , C07K7/04 , C07K14/47
CPC分类号： C07K14/70539 , A61K38/00 , A61K39/0011 , A61P35/00 , C07K4/12 , C07K7/06 , C07K7/08 , C07K14/4748 , C07K14/7051 , C07K14/70571
摘要： The present invention relates to novel peptides derived from 5-hydroxytryptamine receptor 3A (HTR3A), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380491A1
公开(公告)日：2018-10-03
申请号：EP16805187.8
申请日：2016-11-23
发明人： POWLESLAND, Alex , SUN, Meidai , KLEIJNEN, Maurits
IPC分类号： C07K7/06
CPC分类号： C07K7/08 , A61K38/00 , A61P35/00 , C07K7/06 , C07K14/705 , C07K14/7051 , C07K14/70539
摘要： The present invention relates to novel peptides derived from solute carrier family 45 member 2 (SLC45A2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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3.发明公开
公开(公告)号：EP3380503A1
公开(公告)日：2018-10-03
申请号：EP16805194.4
申请日：2016-11-23
IPC分类号： C07K14/47
CPC分类号： C12N9/93 , A61K38/00 , C07K14/4748 , C07K16/40 , G01N33/573 , G01N2333/9015
摘要： The present invention relates to novel peptides derived from Lengsin (LGSN), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380500A1
公开(公告)日：2018-10-03
申请号：EP16805191.0
申请日：2016-11-23
发明人： POWLESLAND, Alex , SUN, Meidai , KLEIJNEN, Maurits
CPC分类号： C07K14/70539 , A61K39/001148 , C07K4/12 , C07K14/12 , C07K14/4748 , C07K14/7051 , C07K2319/21 , G01N33/502
摘要： The present invention relates to novel peptides derived from Structural maintenance of chromosomes protein 1 B (SMC1 B), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380499A1
公开(公告)日：2018-10-03
申请号：EP16805184.5
申请日：2016-11-23
发明人： POWLESLAND, Alex , KLEIJNEN, Maurits , SUN, Meidai
IPC分类号： C07K14/47
CPC分类号： A61K47/6849 , A61K47/42 , A61K47/6855 , A61P35/00 , C07K7/08 , C07K14/4748
摘要： The present invention relates to novel peptides derived from Transient receptor potential cation channel subfamily M member 1 (TRPM1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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