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公开(公告)号：EP3380498A1
公开(公告)日：2018-10-03
申请号：EP16805177.9
申请日：2016-11-23
CPC分类号： A61K38/1774 , A61K35/17 , A61K38/03 , A61K39/0011 , A61P35/00 , C07K14/4748 , C07K14/7051 , C12N15/62 , C12N15/79
摘要： The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen (CT83), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380489A1
公开(公告)日：2018-10-03
申请号：EP16805183.7
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina
CPC分类号： C07K7/06 , A61K39/0011 , A61K2039/605 , C07K14/7051 , C07K14/70539
摘要： The present invention relates to novel peptides derived from DDB1- and CUL4-associated factor 4-like protein 2 (DCAF4L2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380115A1
公开(公告)日：2018-10-03
申请号：EP16805189.4
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina , CHESTER, Fiona
CPC分类号： C07K7/06 , A61K39/0011 , A61K2039/605 , C07K14/47 , C07K14/7051 , C07K14/70539 , C07K16/2833 , C07K2317/32 , G01N33/564
摘要： The present invention relates to novel peptides derived from piwi-like protein 1 (PIWIL1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380509A1
公开(公告)日：2018-10-03
申请号：EP16805179.5
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina , SUN, Meidai
CPC分类号： C07K14/64 , A61K38/00 , A61P35/00 , C07K7/06 , C07K7/08 , C07K14/7051 , C07K14/70539 , C07K19/00 , C40B40/02 , G01N2333/70539
摘要： The present invention relates to novel peptides derived from Prorelaxin H1 (RLN1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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5.发明公开
公开(公告)号：EP3380505A1
公开(公告)日：2018-10-03
申请号：EP16805196.9
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina
IPC分类号： C07K14/47
CPC分类号： C07K14/4748 , C07K14/7051 , C07K14/70539 , C07K16/18 , C07K2319/00 , G01N33/574
摘要： The present invention relates to novel peptides derived from Achaete-scute homolog 2 (ASCL2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380501A1
公开(公告)日：2018-10-03
申请号：EP16805192.8
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina
CPC分类号： C07K14/4748
摘要： The present invention relates to novel peptides derived from Melanoma-associated antigen C (MAGEC1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380116A1
公开(公告)日：2018-10-03
申请号：EP16805190.2
申请日：2016-11-23
发明人： POWLESLAND, Alex , CHESTER, Fiona , POPA, Alina
CPC分类号： C12N9/6445 , A61K38/00 , A61K39/0011 , A61K2039/605 , C07K14/7051 , C07K14/70539 , C07K16/40 , C07K19/00 , C07K2319/00 , G01N33/573
摘要： The present invention relates to novel peptides derived from Kallikrein-4 (KLK4), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380111A1
公开(公告)日：2018-10-03
申请号：EP16805181.1
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina , ADDIS, Philip
IPC分类号： A61K38/04 , C07K7/00 , C07K14/435
CPC分类号： C07K7/06 , A61K38/00 , C07K14/47 , C07K14/70539
摘要： The present invention relates to novel peptides derived from Actin-like protein 8 (ACTL8), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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