公开(公告)号：EP2178871A2

公开(公告)日：2010-04-28

申请号：EP08776202.7

申请日：2008-07-14

申请人： Imperial Chemical Industries Plc.

发明人： BEVINAKATTI, Hanamanthsa, Shankarsa ,  NEWMAN, Christopher, Paul ,  ELLWOOD, Simon ,  SCHROEDER, Martin

IPC分类号： C07D471/04 ,  C07D487/04 ,  C07D495/04 ,  A61K31/33 ,  A61P29/00

CPC分类号： C07D471/04 ,  C07D487/04 ,  C07D495/04

摘要： A process of preparing cyclic ethers is described. The process involves the reaction of at least one organic compound such as a dioi or a polyol which it has at least one pair of hydroxyl groups separated by 4 or 5 carbon atoms, and which is capable of being converted into an ether linkage, with an organic carbonate in the presence of a base. The base is an alkoxy, a carbonate or a hydroxide base or is a mixture of such bases. At least one of the hydroxyl groups of the organic compound is not a tertiary hydroxyl group.