公开(公告)号：EP4331361A1

公开(公告)日：2024-03-06

申请号：EP22796179.4

申请日：2022-04-28

申请人： Incheon National University Research & Business Foundation ,  S&E Bio Co., Ltd.

发明人： CHA, Jae Min ,  KANG, Wu Young ,  KIM, Eun Hee ,  SHIN, Eun Kyoung ,  BAN, Jae Bok

IPC分类号： A01N1/02 ,  C12N1/04 ,  C12N5/00

摘要： The present invention relates to a composition, for freeze-dry protecting extracellular vesicles, capable of preserving the function and characteristics of extracellular vesicles, and an extracellular vesicle freeze-drying method using same. Trehalose and sucrose of the present invention are added to an extracellular vesicle freeze-drying process to solve the problems of crystal growth and redissolution capacity degradation, which are problems in an existing freeze-dry protective agent, and also maintain the unique marker, functional factor expressions and therapeutic effects of the extracellular vesicles, and thus may be variously utilized for producing various therapeutic agents using extracellular vesicles.