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    RECOMBINANT PROTEIN AND PREPARATION METHOD AND APPLICATION THEREOF
    1.
    发明公开
    RECOMBINANT PROTEIN AND PREPARATION METHOD AND APPLICATION THEREOF 审中-公开

    公开(公告)号：EP3336179A1

    公开(公告)日：2018-06-20

    申请号：EP17206585.6

    申请日：2017-12-12

    申请人： Industrial Technology Research Institute

    发明人： HUANG, Yi-Chau ,  LEE, Huai-Lo ,  TSAI, Yu-Yin ,  LIN, Chih-Lung

    IPC分类号： C12N9/00

    摘要： A recombinant protein and a preparation method and application thereof are provided. The recombinant protein includes a peptide, and the peptide includes an amino acid sequence after substitution of the sequence of SEQ ID NO: 1. The substitution includes at least one selected from the group consisting of the following substitutions: the amino acid at position 182 of SEQ ID NO: 1 is substituted with aspartic acid (Asp); the amino acid at position 268 of SEQ ID NO: 1 is substituted with aspartic acid (Asp); and the amino acid at position 384 of SEQ ID NO: 1 is substituted with tyrosine (Tyr). The recombinant protein is suitable for detecting glycated hemoglobin.