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    Sustained release composition and manufacturing method thereof
    2.
    发明公开
    Sustained release composition and manufacturing method thereof 有权
    持续释放组合物及其制造方法

    公开(公告)号：EP2074988A1

    公开(公告)日：2009-07-01

    申请号：EP07025176.4

    申请日：2007-12-28

    申请人： Industrial Technology Research Institute

    发明人： Lu, Jui-Mei ,  Liu, Chia-Wen ,  Lai, Po Hong ,  Lin, John, Jiang, Hann ,  Li, Chiao Pin ,  Cheng, Sung, En ,  Lo, Yo Wen ,  Sheu, Ming-Thau ,  Lin, Min-Ying

    IPC分类号： A61K9/16 ,  A61K9/70

    CPC分类号： A61K9/1647 ,  A61K9/08 ,  A61K9/10 ,  A61K9/1641

    摘要： A sustained release composition comprising a polymer and manufacturing method thereof. The sustained release composition comprises a polymer, a bioactive agent, and a release rate determined agent, wherein the release rate determined agent is dispersed in the sustained release composition to control the release rate of the bioactive agent. The method comprises providing an oil phase comprising a bioactive agent, a polymer, and a release rate determined agent; providing an aqueous phase comprising a surfactant; mixing the oil phase with the aqueous phase to form the sustained release composition having a controlled release effect.

    摘要翻译： 包含聚合物的持续释放组合物及其制造方法。 持续释放组合物包含聚合物，生物活性剂和释放速率确定的试剂，其中释放速率确定的试剂分散在缓释组合物中以控制生物活性剂的释放速率。 该方法包括提供包含生物活性剂，聚合物和释放速率测定剂的油相; 提供包含表面活性剂的水相; 将油相与水相混合以形成具有控释效果的持续释放组合物。