公开(公告)号：EP4056718A1

公开(公告)日：2022-09-14

申请号：EP22161710.3

申请日：2022-03-11

申请人： Industry-Academic Cooperation Foundation, Chosun University

发明人： KIM, Dong Min ,  LEE, You Mi ,  KIM, Choon Mee ,  HWANG, Seong Yeon

IPC分类号： C12Q1/70

摘要： Disclosed herein are a composition for detection of a SARS-CoV-2 viral gene and COVID-19 diagnosis method using RT-PCR. More specifically, provided are a composition for detection of SARS-CoV-2 viral gene, a COVID-19 diagnosis kit comprising the composition, and a method for providing information for diagnosis of COVID-19, wherein the composition comprises: the primer of SEQ ID NO: 1, the primer of SEQ ID NO: 2, and the probe of SEQ ID NO: 3; or the primer of SEQ ID NO: 4, the primer of SEQ ID NO: 5, and the probe of SEQ ID NO: 6. Being able to specifically detect an RdRp or ORF3a gene of SARS-CoV-2 virus, with superiority to conventional detection methods in terms of detection specificity and sensitivity, the composition for detection of a SARS-CoV-2 viral gene and the diagnostic method for COVID-19 using same according to the present disclosure have the effect of promptly and accurately diagnosing COVID-19 through PCR in a simple manner.

公开(公告)号：EP4056717A1

公开(公告)日：2022-09-14

申请号：EP22161705.3

申请日：2022-03-11

申请人： Industry-Academic Cooperation Foundation, Chosun University

发明人： KIM, Dong Min ,  LEE, You Mi ,  KIM, Choon Mee

IPC分类号： C12Q1/689

摘要： Disclosed are a composition for diagnosis of Q fever and a method for diagnosing Q fever by using real-time PCR, more specifically, a composition for detection of Q fever bacteria, the composition including a polynucleotide set containing a primer of SEQ ID NO: 1, a primer of SEQ ID NO: 2, and a probe of SEQ ID NO: 3, or a polynucleotide set containing a primer of SEQ ID NO: 4, a primer of SEQ ID NO: 2, and a probe of SEQ ID NO: 9, a kit for diagnosis of Q fever, the kit including the composition for detection, and an information providing method for diagnosis of Q fever, wherein the composition for detection of Q fever and the method for diagnosis of Q fever by using the same can specifically detect the IS1111 gene of the Q fever bacteria Coxiella burnetii and can promptly and accurately diagnose Q fever through a simple method using real-time PCR due to excellent accuracy and sensitivity compared with existing known detection methods.

公开(公告)号：EP4001438A1

公开(公告)日：2022-05-25

申请号：EP21208319.0

申请日：2021-11-15

申请人： Industry-Academic Cooperation Foundation, Chosun University

发明人： Kim, Dong Min ,  LEE, You Mi ,  KIM, Choon Mee

IPC分类号： C12Q1/689

摘要： Disclosed herein are a composition for diagnosis of leptospirosis and a method for diagnosis of leptospirosis by real-time PCR. Specifically, a composition for detection of a Leptospira bacterium, comprising a pair of primers of SEQ ID NOS: 1 and 2 and a probe of SEQ ID NO: 3, a kit for diagnosis of leptospirosis, comprising the diagnostic composition, and a method for providing information for diagnosis of leptospirosis are provided. The composition for detection of Leptospira spp. and the method for diagnosis of leptospirosis, using the same can specifically detect L. interrogans IS 1500 gene and exhibit excellent accuracy and sensitivity, compared to conventional well-known detection methods. Thus, the simple method through real-time PCR using the composition allows the quick and accurate diagnosis of leptospirosis.