专利检索 ap:("Instituto Biomar S.A.") AND inv:"CANEDO, Librada MariaInstituto Biomar S.A." 第 1 页

1.

发明公开
INDOLOCARBAZOLE ALKALOIDS FROM A MARINE ACTINOMYCETE 有权
标题翻译： INDOLOCARBAZOLALKALOIDE从海洋放线菌

公开(公告)号：EP1189908A1

公开(公告)日：2002-03-27

申请号：EP00940633.1

申请日：2000-06-28

申请人： Instituto Biomar S.A.

发明人： GARCIA GRAVALOS, DoloresPharma Mar S.A. , PEREZ, JuliaInstituto Biomar S.A. , CANEDO, Librada MariaInstituto Biomar S.A. , ROMERO, FranciscoInstituto Biomar S.A. , ESPLIEGO, FernandoInstituto Biomar S.A.

IPC分类号： C07D498/22 , A61K31/553 , A61P35/00

CPC分类号： C07D498/22

摘要： The invention provides compounds of formula (1) wherein R1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and R2 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The invention also relates to a process for obtaining the compounds, compositions containing them and their therapeutic use. The compounds display excellent activity against mammalian cancer cell lines.