公开(公告)号：EP2818179A1

公开(公告)日：2014-12-31

申请号：EP14177983.5

申请日：2003-11-06

申请人： Invion Limited

发明人： Hill, Geoffrey R. ,  Banovic, Tatjana ,  Morton, Halle ,  Cavanagh, Alice Christina

IPC分类号： A61K38/17 ,  A61P37/06

CPC分类号： A61K38/1709 ,  Y10S514/885 ,  A61K2300/00

摘要： The invention is directed to the use of cpn10 in transplantation and particularly to treatment and/or prevention of graft versus host disease. The invention provides a method of administration of cpn10 to a donor and/or recipient animal or cells, tissues or organs derived from the donor, although in a particularly advantageous form treatment of both the donor and recipient animal. The method may further include the administration to the donor and/or recipient animal at least one other immunosuppressive agent to prevent or alleviate graft versus host disease.

摘要翻译： 本发明涉及cpn10在移植中的用途，特别涉及治疗和/或预防移植物抗宿主病。 本发明提供了向供体和/或受体动物或源自供体的细胞，组织或器官施用cpn10的方法，尽管以特别有利的形式治疗供体和受体动物。 该方法还可包括向供体和/或受体动物施用至少一种其它免疫抑制剂以预防或减轻移植物抗宿主病。