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公开(公告)号:EP2121707A1
公开(公告)日:2009-11-25
申请号:EP07848727.9
申请日:2007-12-19
发明人: STANSFIELD, Ian , KOCH, Uwe , HABERMANN, Joerg , NARJES, Frank
IPC分类号: C07D513/04 , C07D513/18 , C07D515/18 , A61K31/407 , A61P31/14
CPC分类号: C07D515/18 , C07D513/04 , C07D513/18
摘要: Compounds of the formula (I) wherein A, B, D, M, Ar, W, X, Y, Z and R1 are as defined herein, are useful in the prevention and treatment of hepatitis C infections. The compounds, their preparation, pharmaceutical compositions containing them and their use in medicine are disclosed.
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公开(公告)号:EP1807397A2
公开(公告)日:2007-07-18
申请号:EP05798382.7
申请日:2005-10-25
发明人: ERCOLANI, Caterina , HABERMANN, Joerg , NARJES, Frank , PONZI, Simona , ROWLEY, Michael , STANSFIELD, Ian
IPC分类号: C07D223/18 , A61K31/407 , A61P31/00
CPC分类号: C07D245/04 , C07D267/22 , C07D487/04 , C07D491/14 , C07D495/14
摘要: The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, R14, R15, A, Ar, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.
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