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公开(公告)号：EP1679965A2
公开(公告)日：2006-07-19
申请号：EP04779628.9
申请日：2004-07-30
CPC分类号： C07H7/06 , Y10S514/866 , Y10S514/909
摘要： This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
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公开(公告)号：EP1680131A2
公开(公告)日：2006-07-19
申请号：EP04779672.7
申请日：2004-07-30
摘要： Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
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公开(公告)号：EP1680414A2
公开(公告)日：2006-07-19
申请号：EP04779629.7
申请日：2004-07-29
IPC分类号： C07D401/04
CPC分类号： C07H15/26
摘要： Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
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公开(公告)号：EP1554240A1
公开(公告)日：2005-07-20
申请号：EP03773302.9
申请日：2003-10-17
IPC分类号： C07C323/52 , C07C323/61 , C07C275/34 , C07C271/56 , A61K31/16
CPC分类号： C07C323/52 , C07C323/44 , C07C2602/08 , C07C2602/10
摘要： This invention features tetralin and indane compounds, compositions containing them, and methods of using them as PPAR alpha modulators to treat or inhibit the progression of, for example, diabetes.
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公开(公告)号：EP2078022B1
公开(公告)日：2011-11-09
申请号：EP07842799.4
申请日：2007-09-19
发明人： XIANG, Min A. , PATEL, Mona , RYBCZYNSKI, Philip , GUNNET, Joseph , DEMAREST, Keith T. , LOOK, Richard , MARYANOFF, Bruce , COSTANZO, Michael J. , YABUT, Stephen C.
IPC分类号： C07D487/10 , A61K31/55 , A61P9/00 , A61P9/12
CPC分类号： C07D487/10
摘要： The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula (I), which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal insufficiency, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
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公开(公告)号：EP1569897A1
公开(公告)日：2005-09-07
申请号：EP03809577.4
申请日：2003-10-17
IPC分类号： C07C323/52 , C07C275/34 , C07C275/28 , A61K31/196 , A61P3/06 , A61P9/10 , A61P9/12
CPC分类号： C07C275/34 , C07C275/28 , C07C323/44 , C07C323/52 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07C2602/10
摘要： The invention features tetralin and indane compounds, compositions containing them, and methods of using them as PPAR alpha modulators to treat or inhibit the progression of, for example, dyslipidemia.
摘要翻译： 本发明具有四氢化萘和茚满化合物，含有它们的组合物，以及将其用作PPARα调节剂来治疗或抑制例如血脂异常的进展的方法。
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7.发明公开
公开(公告)号：EP2078022A1
公开(公告)日：2009-07-15
申请号：EP07842799.4
申请日：2007-09-19
发明人： XIANG, Min A. , PATEL, Mona , RYBCZYNSKI, Philip , GUNNET, Joseph , DEMAREST, Keith T. , LOOK, Richard , MARYANOFF, Bruce , COSTANZO, Michael J. , YABUT, Stephen C.
IPC分类号： C07D487/10 , A61K31/55 , A61P9/00 , A61P9/12
CPC分类号： C07D487/10
摘要： The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula (I), which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal insufficiency, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
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8.发明公开TREATING SYNDROME X WITH SUBSTITUTED TETRALINS AND INDANES 审中-公开印度尼西亚UNG ON ON ROM EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN
公开(公告)号：EP1556344A1
公开(公告)日：2005-07-27
申请号：EP03773286.4
申请日：2003-10-17
IPC分类号： C07C323/52 , A61K31/17 , A61K31/325 , A61P3/04 , A61P3/10 , A61P9/12
CPC分类号： C07C323/52 , C07C275/34 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07C2602/10
摘要： The invention features tetralin and indane compounds of Formula I, compositions containing them, and methods of using them as PPAR alpha modulators to treat or inhibit the progression of, for example, diabetes.
摘要翻译： 本发明具有四氢化萘和茚满化合物，含有它们的组合物，以及使用它们作为PPARα调节剂治疗或抑制例如糖尿病进展的方法。
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