专利检索 ap:("JAPAN as represented by DIRECTOR GENERAL of National Institute of Infectious Diseases") AND inv:"LERTMEMONGKOLCHAI, Ganjana" 第 1 页

1.

发明公开
FLAVIVIRUS CROSS-NEUTRALIZING ANTIBODY AND PHARMACEUTICAL COMPOSITION 审中-公开

公开(公告)号：EP4108773A1

公开(公告)日：2022-12-28

申请号：EP21757741.0

申请日：2021-02-04

申请人： JAPAN as represented by DIRECTOR GENERAL of National Institute of Infectious Diseases

发明人： TAKAHASHI Yoshimasa , NITHICHANON Arnone , MATSUMURA Takayuki , SUZUKI Ryosuke , LIM, Chang Kweng , LERTMEMONGKOLCHAI, Ganjana

IPC分类号： C12N15/13 , A61K39/395 , A61P31/14 , C07K16/10

摘要： Provided is a flavivirus cross neutralizing antibody which has an excellent ability to control infection with suppressed ADE. This is a flavivirus cross neutralizing antibody that specifically binds to domains of E protein of flavivirus and thereby has an ability to control infection with at least two viruses included in the flavivirus. The domains of E protein include a plurality of domains including domain III. The flavivirus includes, for example, Zika virus, dengue virus types 1-4, and Japanese encephalitis virus.