公开(公告)号：EP3526346A1

公开(公告)日：2019-08-21

申请号：EP17791242.5

申请日：2017-10-11

申请人： Janssen Biotech, Inc.

发明人： ARMSTRONG, Anthony ,  BECK, Stephen ,  CHAVEZ, Jose Antonio ,  CHIN, Chen-Ni ,  DINH, Thai ,  FURMAN, Jennifer ,  HUSOVSKY, Matt ,  LIN-SCHMIDT, Xiefan ,  MULLICAN, Shannon ,  RANGWALA, Shamina ,  SOUTH, Vicki

IPC分类号： C12Q1/68 ,  A61K38/18

公开(公告)号：EP2825199A1

公开(公告)日：2015-01-21

申请号：EP13760575.4

申请日：2013-03-11

申请人： Janssen Biotech, Inc.

发明人： MOORES, Sheri ,  PARDINAS, Jose ,  ZIOBER, Barry L. ,  CHI, Ellen ,  DINH, Thai ,  EDAVETTAL, Suzanne ,  FENTON, Sandra ,  HAMEL, Damon ,  ZHOU, H. Mimi

IPC分类号： A61K39/395

CPC分类号： C07K16/40 ,  C07K2317/21 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92

摘要： Antibodies and compositions capable of binding and, in a particular aspect, inhibiting the lysophosphatidylipase D activity of human autotaxin protein. The antibodies or are useful in detecting human autotaxin protein and treating diseases and disorders associated with unwanted lysophosphatidylipase D and the presence of lysophosphatidic acid, such as cancer and pulmonary diseases.