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公开(公告)号：EP2709989B1
公开(公告)日：2017-12-20
申请号：EP12721852.7
申请日：2012-05-18
发明人： MC GOWAN, David , RABOISSON, Pierre, Jean-Marie, Bernard , JONCKERS, Tim, Hugo, Maria , LAST, Stefaan, Julien , EMBRECHTS, Werner , PIETERS, Serge, Maria, Aloysius
IPC分类号： C07D239/95 , A61K31/517 , A61P31/00
CPC分类号： C07D491/056 , C07D239/95 , C07D295/192 , C07D401/06 , C07D403/04
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2.发明授权
公开(公告)号：EP2903967B1
公开(公告)日：2018-09-12
申请号：EP13779156.2
申请日：2013-10-03
发明人： MC GOWAN, David Craig , PIETERS, Serge Maria Aloysius , EMBRECHTS, Werner , LAST, Stefaan Julien , JONCKERS, Tim Hugo Maria , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D213/75 , A61K31/505 , A61P31/12 , C07D239/48 , C07D239/47
CPC分类号： C07D239/47 , C07D213/75 , C07D239/48
摘要： This invention relates to acylaminopyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
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公开(公告)号：EP2776439B1
公开(公告)日：2018-07-04
申请号：EP12784574.1
申请日：2012-11-08
发明人： BONFANTI, Jean-François , DOUBLET, Frédéric Marc Maurice , EMBRECHTS, Werner , FORTIN, Jérôme Michel Claude , MC GOWAN, David Craig , MULLER, Philippe , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D473/34 , A61K31/522 , A61P31/12 , C07D519/00 , C07D473/16 , C07F9/6561
CPC分类号： C07D473/34 , C07D473/16 , C07D519/00 , C07F9/65616
摘要： The present invention relates to purine derivatives of formula (I), processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
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4.发明公开PYRROLO[3,2-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES 有权吡咯并[3,2-D]嘧啶衍生物对病毒感染和其他疾病治疗
公开(公告)号：EP2906563A1
公开(公告)日：2015-08-19
申请号：EP13779766.8
申请日：2013-10-09
发明人： MC GOWAN, David Craig , LAST, Stefaan Julien , PIETERS, Serge Maria Aloysius , EMBRECHTS, Werner , JONCKERS, Tim Hugo Maria , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D487/04 , A61K31/519 , A61P29/00 , A61P31/12 , A61P37/00
CPC分类号： C07D487/04 , A61K31/407 , A61K31/519 , C07D519/00
摘要： This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
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5.发明授权PYRROLO[3,2-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES 有权吡咯并[3,2-D]嘧啶衍生物用于治疗病毒感染和其它疾病
公开(公告)号：EP2906563B1
公开(公告)日：2018-02-28
申请号：EP13779766.8
申请日：2013-10-09
发明人： MC GOWAN, David Craig , LAST, Stefaan Julien , PIETERS, Serge Maria Aloysius , EMBRECHTS, Werner , JONCKERS, Tim Hugo Maria , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D487/04 , A61K31/519 , A61P29/00 , A61P31/12 , A61P37/00
CPC分类号： C07D487/04 , A61K31/407 , A61K31/519 , A61P31/12 , C07D519/00
摘要： This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
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6.发明授权HETEROCYCLIC SUBSTITUTED 2-AMINO-QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS 有权杂环取代的2-氨基喹唑啉衍生物用于治疗病毒感染
公开(公告)号：EP2925729B1
公开(公告)日：2017-10-18
申请号：EP13789821.9
申请日：2013-11-15
发明人： LAST, Stefaan, Julien , MC GOWAN, David, Craig , EMBRECHTS, Werner , PIETERS, Serge, Maria, Aloysius , JONCKERS, Tim, Hugo, Maria , RABOISSON, Pierre, Jean-Marie, Bernard
IPC分类号： C07D239/95 , A61K31/505 , A61P31/12
CPC分类号： C07D239/84 , C07D239/95 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
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7.发明公开PYRROLO [3,2-D] PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES 有权PYRROLO [3,2-D] PYRIMIDIN-DERIVATE ZUR BEHANDLUNG VON VIRUSINFEKTIONEN UND ANDEREN ERKRANKUNGEN
公开(公告)号：EP3030563A1
公开(公告)日：2016-06-15
申请号：EP14738751.8
申请日：2014-06-26
发明人： MC GOWAN, David Craig , PIETERS, Serge Maria Aloysius , LAST, Stefaan Julien , EMBRECHTS, Werner , JONCKERS, Tim Hugo Maria , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D487/04 , A61K31/519 , A61P31/12
CPC分类号： C07D487/04
摘要： This invention concerns pyrrolo[3,2-
d ]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and /or therapy of diseases.摘要翻译： 本发明涉及吡咯并[3,2-d]嘧啶衍生物，其制备方法，药物组合物及其在治疗和/或治疗疾病中的用途。
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8.发明公开HETEROCYCLIC SUBSTITUTED 2-AMINO-QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS 有权杂环化合物替代品2-AMINO-CHINAZOLINDERIVATE ZUR BEHANDLUNG VON VIRUSINFEKTIONEN
公开(公告)号：EP2925729A1
公开(公告)日：2015-10-07
申请号：EP13789821.9
申请日：2013-11-15
发明人： LAST, Stefaan, Julien , MC GOWAN, David, Craig , EMBRECHTS, Werner , PIETERS, Serge, Maria, Aloysius , JONCKERS, Tim, Hugo, Maria , RABOISSON, Pierre, Jean-Marie, Bernard
IPC分类号： C07D239/95 , A61K31/505 , A61P31/12
CPC分类号： C07D239/84 , C07D239/95 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
摘要： This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
摘要翻译： 本发明涉及杂环取代的2-氨基 - 喹唑啉衍生物，其制备方法，药物组合物及其在治疗病毒感染中的用途。
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9.发明公开ACYLAMINOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES 有权ACYLAMINOPYRIMIDINDERIVATE ZUR BEHANDLUNG VON VIRUSINFEKTIONEN UND WEITEREN ERKRANKUNGEN
公开(公告)号：EP2903967A1
公开(公告)日：2015-08-12
申请号：EP13779156.2
申请日：2013-10-03
发明人： MC GOWAN, David Craig , PIETERS, Serge Maria Aloysius , EMBRECHTS, Werner , LAST, Stefaan Julien , JONCKERS, Tim Hugo Maria , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D213/75 , A61K31/505 , A61P31/12 , C07D239/48
CPC分类号： C07D239/47 , C07D213/75 , C07D239/48
摘要： This invention relates to acylaminopyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
摘要翻译： 本发明涉及酰氨基嘧啶衍生物，其制备方法，药物组合物及其在治疗中的应用。
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公开(公告)号：EP2694484B1
公开(公告)日：2018-07-18
申请号：EP12712666.2
申请日：2012-04-10
发明人： MC GOWAN, David , RABOISSON, Pierre Jean-Marie Bernard , EMBRECHTS, Werner , JONCKERS, Tim, Hugo, Maria , LAST, Stefaan, Julien , PIETERS, Serge, Maria, Aloysius , VLACH, Jaromir
IPC分类号： C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , A61K31/505 , A61K31/506
CPC分类号： A61K31/505 , A61K31/506 , A61K31/5377 , C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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