公开(公告)号：EP2118091B1

公开(公告)日：2015-04-15

申请号：EP08708826.6

申请日：2008-02-08

申请人： Janssen Sciences Ireland UC ,  Medivir AB

发明人： RABOISSON, Pierre Jean-Marie Bernard ,  BELFRAGE, Anna, Karin, Gertrud, Linnea ,  CLASSON, Björn, Olof ,  LINDQUIST, Karin, Charlotta ,  NILSSON, Karl, Magnus ,  ROSENQUIST, Åsa, Annica, Kristina ,  SAMUELSSON, Bengt, Bertil ,  WÄHLING, Horst, Jürgen

IPC分类号： C07D403/12 ,  C07K5/06

CPC分类号： C07K5/06165 ,  A61K38/00 ,  C07D403/12 ,  Y02A50/385 ,  Y02A50/387

摘要： Compounds of the formula I: including a stereoisomer thereof, or an N-oxide, a pharmaceutically acceptable addition salt, or a pharmaceutically acceptable addition solvate thereof; useful as HCV inhibitors; processes for preparing these compounds as well as pharmaceutical compositions comprising these compounds as active ingredient.

公开(公告)号：EP2118091A1

公开(公告)日：2009-11-18

申请号：EP08708826.6

申请日：2008-02-08

申请人： Tibotec Pharmaceuticals ,  Medivir AB

发明人： RABOISSON, Pierre Jean-Marie Bernard ,  BELFRAGE, Anna, Karin, Gertrud, Linnea ,  CLASSON, Björn, Olof ,  LINDQUIST, Karin, Charlotta ,  NILSSON, Karl, Magnus ,  ROSENQUIST, Åsa, Annica, Kristina ,  SAMUELSSON, Bengt, Bertil ,  WÄHLING, Horst, Jürgen

IPC分类号： C07D403/12 ,  C07K5/06

CPC分类号： C07K5/06165 ,  A61K38/00 ,  C07D403/12 ,  Y02A50/385 ,  Y02A50/387

摘要： Compounds of the formula I: including a stereoisomer thereof, or an N-oxide, a pharmaceutically acceptable addition salt, or a pharmaceutically acceptable addition solvate thereof; useful as HCV inhibitors; processes for preparing these compounds as well as pharmaceutical compositions comprising these compounds as active ingredient.

公开(公告)号：EP2111396B1

公开(公告)日：2013-08-07

申请号：EP08708828.2

申请日：2008-02-08

申请人： Janssen R&D Ireland ,  Medivir AB

发明人： RABOISSON, Pierre Jean-Marie Bernard ,  ANTONOV, Dmitry ,  AYESA ALVAREZ, Susana ,  BELFRAGE, Anna, Karin, Gertrud, Linnea ,  JÖNSSON, Carl, Erik, Daniel ,  MC GOWAN, David, Craig ,  NILSSON, Karl, Magnus ,  ROSENQUIST, Åsa, Annica, Kristina ,  SAMUELSSON, Bengt, Bertil

IPC分类号： C07D245/04 ,  C07D255/04 ,  C07D401/12 ,  C07D403/12 ,  C07D417/12 ,  C07D498/04 ,  C07D498/14 ,  A61K31/538 ,  A61P31/14

CPC分类号： C07D245/04 ,  C07D255/04 ,  C07D401/12 ,  C07D403/12 ,  C07D417/12 ,  C07D498/04 ,  C07D498/14

公开(公告)号：EP2111396A1

公开(公告)日：2009-10-28

申请号：EP08708828.2

申请日：2008-02-08

申请人： Tibotec Pharmaceuticals Ltd. ,  Medivir AB

发明人： RABOISSON, Pierre Jean-Marie Bernard ,  ANTONOV, Dmitry ,  AYESA ALVAREZ, Susana ,  BELFRAGE, Anna, Karin, Gertrud, Linnea ,  JÖNSSON, Carl, Erik, Daniel ,  MC GOWAN, David, Craig ,  NILSSON, Karl, Magnus ,  ROSENQUIST, Åsa, Annica, Kristina ,  SAMUELSSON, Bengt, Bertil

IPC分类号： C07D245/04 ,  C07D255/04 ,  C07D401/12 ,  C07D403/12 ,  C07D417/12 ,  C07D498/04 ,  C07D498/14 ,  A61K31/538 ,  A61P31/14

CPC分类号： C07D245/04 ,  C07D255/04 ,  C07D401/12 ,  C07D403/12 ,  C07D417/12 ,  C07D498/04 ,  C07D498/14

摘要： Compounds of the Formula (I) including a stereoisomer thereof, or an N-oxide, a pharmaceutically acceptable addition salt, or a pharmaceutically acceptable addition solvate thereof;usefulas HCV inhibitors; processes for preparing these compounds as well as pharmaceutical compositions comprising these compounds as active ingredient.

摘要翻译： 包含其立体异构体或N-氧化物，药学上可接受的加成盐或其药学上可接受的加成溶剂化物的式（I）化合物;有用的HCV抑制剂; 制备这些化合物的方法以及包含这些化合物作为活性成分的药物组合物。