公开(公告)号：EP3693390A1

公开(公告)日：2020-08-12

申请号：EP18864490.0

申请日：2018-10-03

申请人： Joint Stock Company "Biocad"

发明人： SOLOVYEV, Kirill Vladimirovich ,  ULITIN, Andrei Borisovich ,  NEMANKIN, Timofey Aleksandrovich ,  SOLOVYEV, Valery Vladimirovich ,  MOROZOV, Dmitry Valentinovich

IPC分类号： C07K16/28 ,  C12N15/13 ,  C12N15/63 ,  C12N5/10 ,  A61K39/395 ,  A61P35/00

摘要： The present invention relates to the field of bioengineering, specifically to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to antibodies that bind specifically to CD47 and PD-L1. The invention also relates to a nucleic acid that codes for the given antibody or for the antigen-binding fragment thereof, to an expression vector, to a method of producing the antibody, and to a use of the aforementioned antibodies and compositions in cancer treatment.