公开(公告)号：EP3277683A1

公开(公告)日：2018-02-07

申请号：EP16723536.5

申请日：2016-03-30

申请人： Jubilant Biosys Ltd.

发明人： VADIVELU, Saravanan ,  RAJAGOPAL, Sridharan ,  CHINNAPATTU, Murugan ,  GONDRALA, Pavan Kumar ,  SIVANANDHAN, Dhanalakshmi ,  MULAKALA, Chandrika

IPC分类号： C07D471/04 ,  C07D491/04 ,  A61K31/55 ,  A61K31/4353 ,  A61P35/00

CPC分类号： C07D491/04 ,  A61K45/06 ,  A61K2300/00 ,  A61P35/00 ,  C07D471/04

摘要： The present disclosure described heterocyclic compounds of Formula I or, its stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms and pharmaceutically active derivative thereof and pharmaceutical compositions containing them as the active ingredient. The present disclosure also describes the synthesis and characterization of aforementioned compounds to exhibit high anticancer activity. The compounds of the present disclosure are useful as medicaments and their use in the manufacture of medicaments for treatment, prevention or suppression of diseases, and conditions mediated by one or more BET family of bromodomains.

公开(公告)号：EP3455204A1

公开(公告)日：2019-03-20

申请号：EP17737887.4

申请日：2017-05-08

申请人： Jubilant Biosys Ltd.

发明人： RAJAGOPAL, Sridharan ,  HALLUR, Mahanandeesha S. ,  DEWANG, Purushottam ,  MURUGAN, Kannan ,  KUMAR C.H., Durga Prasanna ,  IYER, Pravin ,  MULAKALA, Chandrika ,  SIVANANDHAN, Dhanalakshmi ,  NAIR, Sreekala ,  ZAINUDDIN, Mohd. ,  TANTRY, Subramanyam Janardhan ,  GAJENDRAN, Chandru ,  RAJAGOPAL, Sriram

IPC分类号： C07C259/06 ,  C07D261/08 ,  C07D239/26 ,  C07D401/04 ,  C07D403/12 ,  C07D401/14 ,  C07D413/14 ,  C07C259/08 ,  C07C259/10 ,  C07D231/12 ,  C07D233/64 ,  A61K31/165 ,  A61P35/00 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  C07D249/04 ,  C07D487/04 ,  C07D205/04 ,  C07D211/26 ,  C07D211/58