公开(公告)号：EP4194456A1

公开(公告)日：2023-06-14

申请号：EP21213131.2

申请日：2021-12-08

申请人： Julius-Maximilians-Universität Würzburg

发明人： Dandekar, Thomas ,  Sarukhanyan, Edita

IPC分类号： C07D471/06 ,  A61P25/28 ,  C07D311/92 ,  C07D471/16 ,  C07D491/16 ,  C07D493/16 ,  C07F9/48 ,  C07F9/6571

摘要： The present invention relates to a new compound according to formula (I) as well as to the use of this compound in medicine, in the prevention of the aggregation of phosphorylated Tau proteins, the treatment or prevention of a tauopathy and in the treatment or prevention of a neurodegenerative disease, preferably selected from the group consisting of Primary age-related tauopathy (PART) dementia, Chronic traumatic encephalopathy, Progressive supranuclear palsy, Corticobasal degeneration and Alzheimer's disease, more preferably Alzheimer's disease.