公开(公告)号：EP0835667A1

公开(公告)日：1998-04-15

申请号：EP97907319.4

申请日：1997-03-14

申请人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute

发明人： 2CHIDA, Takanori ,  KAETSU, Hiroshi ,  FUKUNAGA, Nobuto ,  SHINYA, Noriko ,  SAKAMOTO, Takahiro

IPC分类号： A61L25/00 ,  A61B17/00

CPC分类号： A61L24/106 ,  A61B17/00491 ,  A61B2017/00495 ,  Y10S514/822

摘要： An adhesive for tissue capable of uniformly forming a high concentration of fibrin so as to provide a high closing effect is disclosed. The adhesive for tissue comprises a fibrinogen solution and a thrombin solution which solutions are separated from each other. The adhesive is to be mixed and spray coated together with a sterile gas and has a volume ratio of the fibrinogen solution to the thrombin solution of about 2:1 to 10:1. This adhesive is to be sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or anima l.

摘要翻译： 公开了能够均匀地形成高浓度纤维蛋白以提供高闭合效果的组织粘合剂。 用于组织的粘合剂包括纤维蛋白原溶液和溶液彼此分离的凝血酶溶液。 将粘合剂混合并用无菌气体喷雾涂布，并且纤维蛋白原溶液与凝血酶溶液的体积比为约2:1至10:1。 该粘合剂将与无菌气体一起喷雾以用于人或动物的活组织的粘附或闭合。

公开(公告)号：EP1588722A1

公开(公告)日：2005-10-26

申请号：EP04702784.2

申请日：2004-01-16

申请人： Juridical Foundation The Chemo-Sero-Therapeutic Research Institute

发明人： UCHIDA, Takanori ,  SHINYA, Noriko ,  KAETSU, Hiroshi

IPC分类号： A61L15/00 ,  A61F13/00

CPC分类号： A61L15/32 ,  A61F13/36 ,  A61F2013/00472 ,  A61L15/26 ,  A61L2400/04 ,  Y10T442/2508 ,  Y10T442/2525 ,  Y10T442/2861 ,  Y10T442/696 ,  C08L65/04

摘要： A safe and effective hemostatic material is provided. A hemostatic material comprising as an effective ingredient thrombin and fibrinogen characterized in that a bioabsorbable synthetic nonwoven fabric is used as a supporting material. The use of the hemostatic material of the present invention allows for quick and thorough hemostasis for both projectile bleeding and exudative bleeding.

摘要翻译： 提供安全有效的止血材料。 一种止血材料，其包含作为有效成分的凝血酶和纤维蛋白原，其特征在于使用生物可吸收的合成非织造织物作为支持材料。 使用本发明的止血材料可以快速和彻底地止血用于射弹出血和渗出性出血。

公开(公告)号：EP0835667B1

公开(公告)日：2005-11-09

申请号：EP97907319.4

申请日：1997-03-14

申请人： Juridical Foundation The Chemo-Sero-Therapeutic Research Institute

发明人： UCHIDA, Takanori ,  KAETSU, Hiroshi ,  FUKUNAGA, Nobuto ,  SHINYA, Noriko ,  SAKAMOTO, Takahiro

IPC分类号： A61L24/10

CPC分类号： A61L24/106 ,  A61B17/00491 ,  A61B2017/00495 ,  Y10S514/822

摘要： A tissue adhesive capable of forming fibrins uniformly at high density, and exhibiting marked closing effect. This tissue adhesive is mixed with an aseptic gas and the mixture is applied to tissue. The tissue adhesive comprises separated fibrinogen solution and thrombin solution. The volume ratio of the fibrinogen solution to the thrombin solution is 2:1-10:1. This tissue adhesive is used to stick living tissue of a human being or an animal or to close the same.