公开(公告)号：EP0745392B1

公开(公告)日：2001-10-24

申请号：EP95908372.6

申请日：1995-02-13

申请人： KANEBO LTD. ,  UNIMEDICAL, INC.

发明人： TANAKA, Masaya ,  MORIMOTO, Yasuo ,  HARADA, Shoichi ,  YAMASHITA, Sadashi

IPC分类号： A61L15/28

CPC分类号： A61L15/42 ,  A61L15/225 ,  A61L15/28 ,  A61L15/58 ,  C08L5/00

摘要： A wound covering material comprising 1 part by weight of glucomannan, 0.20-0.99 part by weight of a solubility modifier comprising pullulan or carrageenan, 0.10-12 parts by weight of a physiologically acceptable tacky synthetic polymer base, and 0.20-20 parts by weight of at least one plasticizer selected from the group consisting of polyhydric alcohol, sugar alcohol, monosaccharide, disaccharide and oligosaccharide.

公开(公告)号：EP0826371A1

公开(公告)日：1998-03-04

申请号：EP96910219.3

申请日：1996-04-22

申请人： KANEBO LTD.

发明人： TAKAHASHI, Yoshiteru ,  HARADA, Shoichi ,  INAGI, Toshio ,  MADA, Akira ,  TAKENO, Satoshi ,  SAITO, Tadayuki

IPC分类号： A61K31/55

CPC分类号： A61K31/551 ,  A61K9/0014 ,  A61K31/5513 ,  A61K47/06 ,  C07D403/04

摘要： An external preparation which comprises (a) emedastine or a pharmaceutically acceptable salt thereof and (b) one or more bases selected from the group consisting of liquid paraffin, light liquid paraffin and gelled hydrocarbons. The preparation is chemically stable and suffers from little color change and no decrease in the content of the active ingredient during storage. Also, it suffers from little morphological change and remains physically stable, thus showing a high storage stability. When applied, the preparation exerts an antihistaminic effect. It causes scarcely any skin irritation and thus shows a high safety. Accordingly, the preparation is useful in the topical treatment of allergic diseases, in particular, urticaria, eczema/dermatitis, pruritus cutaneus, prurigo, etc.

摘要翻译： 一种外用制剂，其包含（a）依达辛汀或其药学上可接受的盐和（b）一种或多种选自液体石蜡，轻液体石蜡和凝胶化烃的碱。 该制剂是化学稳定的，并且在储存期间几乎没有颜色变化并且活性成分的含量没有降低。 此外，它具有很小的形态变化并且保持物理稳定，因此显示出高的储存稳定性。 使用时，制剂会发挥抗组胺作用。 它几乎不会引起任何皮肤刺激，从而显示出高安全性。 因此，该制剂可用于局部治疗过敏性疾病，特别是荨麻疹，湿疹/皮炎，皮肤瘙痒症，痒疹等。

公开(公告)号：EP0745392A1

公开(公告)日：1996-12-04

申请号：EP95908372.6

申请日：1995-02-13

申请人： KANEBO LTD. ,  UNICOLLOID, INC.

发明人： TANAKA, Masaya ,  MORIMOTO, Yasuo ,  HARADA, Shoichi ,  YAMASHITA, Sadashi

IPC分类号： A61L15/28

CPC分类号： A61L15/42 ,  A61L15/225 ,  A61L15/28 ,  A61L15/58 ,  C08L5/00

摘要： A wound covering material comprising 1 part by weight of glucomannan, 0.20-0.99 part by weight of a solubility modifier comprising pullulan or carrageenan, 0.10-12 parts by weight of physiologically acceptable adhesive polymer base, and 0.20-20 parts by weight of at least one plasticizer selected from the group consisting of polyhydric alcohols, sugar alcohols, monosaccharides, disaccharides and oligosaccharides.

摘要翻译： 包含1重量份葡甘露聚糖，0.20-0.99重量份的包含支链淀粉或角叉菜胶的溶解性改性剂，0.10-12重量份的生理上可接受的粘合剂聚合物基质和至少0.20-20重量份的伤口覆盖材料 一种选自多元醇，糖醇，单糖，二糖和寡糖的增塑剂。