公开(公告)号：EP0111560A4

公开(公告)日：1987-02-03

申请号：EP83902361

申请日：1983-06-14

申请人： KEY PHARMA

发明人： CHARLES HSIAO

IPC分类号： A61K9/22 ,  A61K9/50 ,  A61K9/62 ,  A61K31/60 ,  A61K9/36

CPC分类号： A61K31/60 ,  A61K9/5047

摘要： A sustained release aspirin dosage form permits the continuous delivery of aspiring into the gastrointestinal tract for a period of at least eight hours. The sustained release aspirin dosage form comprises a plurality of polymerically coated aspirin crystals each of which comprises an aspirin seed. The majority of aspirin seeds have a mesh size of from about 30 to about 60 mesh. Each of the aspirin seeds is individually coated with a polymeric mixture, which comprises from about 1.5 to about 15 parts by weight ethylcellulose and about one part by weight hydroxypropylcellulose.